6-Amino-2-(2-aminoethyl)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 6-Amino-2-(2-aminoethyl)-1,3-dioxobenzo[de]isoquinoline-5,8-disulfonic acid
• 化学式: C₁₄H₁₃N₃O₈S₂
• 分子量: 415.4
• InChiKey: PEYOBGYEYBGURJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  215
• 氢给体数：
  4
• 氢受体数：
  10

文献信息

• MALTOTRIOSE METABOLIZING MUTANTS OF SACCHAROMYCES EUBAYANUS
  申请人：Heineken Supply Chain B.V.

  公开号：EP3626838A1

  公开（公告）日：2020-03-25

  The invention relates to a mutant of Saccharomyces eubayanus that is able to ferment maltotriose, and to the use of this mutant for producing hybrid yeast and the resulting hybrid yeast. The invention relates to methods of producing a fermented beer product by employing said mutant and/or said hybrid yeast.

  本发明涉及一种能够发酵麦芽三糖的乌巴酵母突变体，以及使用该突变体生产杂交酵母和由此产生的杂交酵母。本发明涉及利用所述突变体和/或所述杂交酵母生产发酵啤酒产品的方法。
• NANOPARTICLES WITH ACTIVE TARGETING
  申请人：Cristal Delivery B.V.

  公开号：US20190298855A1

  公开（公告）日：2019-10-03

  The present invention is directed to particle comprising a drug and a ligand, and to method of making them and use thereof. Particularly, the present invention results in the covalent entrapment of drug(s) in high amounts in polymer carriers, such as (nano)particle, microspheres and other types of polymer devices for controlled release. The polymer carriers or devices can be decorated with ligands, allowing for targeting specific tissues and/or (non-) invasive monitoring.
• Inverse Agonistic Anti-US28 Antibodies
  申请人：Stichting VU

  公开号：US20210032316A1

  公开（公告）日：2021-02-04

  The invention relates to a novel class of antagonistic and inverse agonistic anti-US28 antibodies, more specifically to single heavy chain variable domain antibodies (VHH) and variants and modifications thereof. The invention further relates to methods for producing these antibodies and to the use of the antibodies in methods for diagnostic and therapeutic purposes, especially for treatment of an individual suffering from a CMV-positive tumor such as glioblastoma.
• IDENTIFICATION OF RARE PRODUCTS OF CROSSING ORGANISMS
  申请人：Heineken Supply Chain B.V.

  公开号：US20210246415A1

  公开（公告）日：2021-08-12

  The invention relates to methods for identifying a hybrid organism, based on staining of parent cells with a dye, preferably a fluorescent dye. A preferred dye is a succinimidyl ester-coupled dye. The invention further relates to the resulting hybrid organism, preferably an interspecies hybrid organism, that is labelled with a dye.