2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)imidazo[1,2-a]pyrimidine | 693219-80-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• 英文名称: 2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)imidazo[1,2-a]pyrimidine
• 英文别名: 2-(2,3-Dihydro-1,4-benzodioxin-6-yl)imidazo[1,2-a]pyrimidine
• CAS: 693219-80-6
• 化学式: C₁₄H₁₁N₃O₂
• mdl: MFCD02681856
• 分子量: 253.26
• InChiKey: OKWKCPGIDMIJJC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  48.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Antibacterial compounds
  申请人：DISCUVA LTD.

  公开号：US11345694B2

  公开（公告）日：2022-05-31

  The present invention relates to compounds of general formula (II), to compositions comprising these compounds and to methods of treating Enterobacteriaceae bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Enterobacteriaceae.

  本发明涉及通式（II）化合物、包含这些化合物的组合物以及使用这些化合物治疗肠杆菌科细菌疾病和感染的方法。这些化合物可用于治疗由肠杆菌科细菌引起的感染和疾病。
• ANTIBACTERIAL COMPOUNDS
  申请人：DISCUVA LTD.

  公开号：US20210163460A1

  公开（公告）日：2021-06-03

  The present invention relates to compounds of general formula (II), to compositions comprising these compounds and to methods of treating Enterobacteriaceae bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Enterobacteriaceae.