3-Chloro-4-(2,4-dioxopentan-3-yl)naphthalene-1,2-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-Chloro-4-(2,4-dioxopentan-3-yl)naphthalene-1,2-dione
• 化学式: C₁₅H₁₁ClO₄
• 分子量: 290.7
• InChiKey: PNZRFKFFKPDCLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  68.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Methods for Screening for Antibiotic Compounds
  申请人：Cheung Ambrose

  公开号：US20120115157A1

  公开（公告）日：2012-05-10

  The present invention is a method for screening drugs for antibiotic activity by screening a drug for activity to disrupt a toxin-antitoxin complex in a bacterial cell.
• Compositions for Treating Bacterial Infections
  申请人：Cheung Ambrose

  公开号：US20120122877A1

  公开（公告）日：2012-05-17

  The present invention is antibiotic compositions having the ability to disrupt a MazEF complex in S. aureus . The compositions also have the ability to inhibit growth of S. aureus and as such are useful as antibiotic compounds.
• US9999617B2
  申请人：——

  公开号：US9999617B2

  公开（公告）日：2018-06-19
• [EN] COMPOSITIONS FOR TREATING BACTERIAL INFECTIONS<br/>[FR] COMPOSITIONS POUR TRAITER DES INFECTIONS BACTÉRIENNES
  申请人：DARTMOUTH COLLEGE

  公开号：WO2011002951A1

  公开（公告）日：2011-01-06

  The present invention is antibiotic compositions having the ability to disrupt a MazEF complex in S. aureus. The compositions also have the ability to inhibit growth of S. aureus and as such are useful as antibiotic compounds.