6-氨基-1H-吲唑-3-羧酸甲酯 | 851652-52-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 中文名称: 6-氨基-1H-吲唑-3-羧酸甲酯
• 英文名称: Methyl 2-(6-amino-1H-indazol-3-yl)acetate
• 英文别名: methyl 2-(6-amino-2H-indazol-3-yl)acetate
• CAS: 851652-52-3
• 化学式: C₁₀H₁₁N₃O₂
• 分子量: 205.21
• InChiKey: OETOCTOYVGFUJH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  81
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES
  申请人：Rigel Pharmaceuticals, Inc.

  公开号：EP1471915A2

  公开（公告）日：2004-11-03
• EP1471915A4
  申请人：——

  公开号：EP1471915A4

  公开（公告）日：2006-02-15
• [EN] 2,4-PYRIMIDINEDIAMINE COMPOUNDS AND THEIR USES<br/>[FR] COMPOSES 2,4-PYRIMIDINEDIAMINE ET LEURS UTILISATIONS
  申请人：RIGEL PHARMACEUTICALS INC

  公开号：WO2003063794A2

  公开（公告）日：2003-08-07

  The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signaling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compunds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signaling cascades.