N-pentyl-thioacetamide | 98430-63-8

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代酰胺
• 英文名称: N-pentyl-thioacetamide
• 英文别名: Thioessigsaeure-pentylamid；N-Pentyl-thioacetamid；N-pentylethanethioamide
• CAS: 98430-63-8
• 化学式: C₇H₁₅NS
• mdl: MFCD19222439
• 分子量: 145.269
• InChiKey: GSPCJHBYNIADIS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  44.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-庚酮肟 在 吡啶 、 苯磺酰氯 作用下， 生成 N-pentyl-thioacetamide
  参考文献：
  名称：

  Huisgen; Witte, Chemische Berichte, 1958, vol. 91, p. 972,974

  摘要：

  DOI：

文献信息

• [EN] SPIROPYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE<br/>[FR] INHIBITEURS DE BÊTA-SÉCRÉTASE DE TYPE SPIROPYRROLIDINE POUR LE TRAITEMENT DE LA MALADIE D'ALZHEIMER
  申请人：MERCK SHARP & DOHME

  公开号：WO2010094242A1

  公开（公告）日：2010-08-26

  The present invention is directed to spiropyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

  本发明涉及式(I)的螺环吡咯烷化合物，它们是β-分泌酶的抑制剂，并且在治疗涉及β-分泌酶的疾病，如阿尔茨海默病中有用。该发明还涉及包含这些化合物的药物组合物，以及在治疗涉及β-分泌酶的这类疾病中使用这些化合物和组合物。
• [EN] INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES<br/>[FR] COMPOSÉS INSECTICIDES À BASE DE DÉRIVÉS D'ARYLTHIACÉTAMIDE
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2012156400A1

  公开（公告）日：2012-11-22

  The present invention provides compounds of formula (I) wherein R1, R2, R3, R4, G1, n, A1, A2, A3, A4, Y1, Y2, and Y3 are as defined in the claims. The invention also relates to processes and intermediates for preparing these compounds, to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising these compounds and to methods of using these compounds to control insect, acarine, nematode and mollusc pests.

  本发明提供了式（I）的化合物，其中R1、R2、R3、R4、G1、n、A1、A2、A3、A4、Y1、Y2和Y3如权利要求中所定义。该发明还涉及用于制备这些化合物的过程和中间体，包括这些化合物的杀虫剂、杀螨剂、杀线虫剂和杀软体动物剂组合物，以及使用这些化合物控制昆虫、螨虫、线虫和软体动物害虫的方法。
• SUBSTANTIALLY PURE SALTS OF FEBUXOSTAT AND PROCESSES FOR PREPARATION THEREOF
  申请人：Dwivedi Shriprakash Dhar

  公开号：US20130190366A1

  公开（公告）日：2013-07-25

  Substantially pure salts of febuxostat of Formula (IA): wherein Y is Na + , K + , Li + , Mg 2+ , Ca 2+ , Zn 2+ , Ba 2+ , Sr 2+ , choline, epolamine and N + (R) 4 and processes for preparation thereof are disclosed.

  本发明公开了Formula (IA)的febuxostat的基本纯盐：其中Y为Na+、K+、Li+、Mg2+、Ca2+、Zn2+、Ba2+、Sr2+、胆碱、epolamine和N+（R）4，以及其制备方法。
• Substituted-amido derivatives, method for preparation of the same and phytopathogenic fungicides containing the same
  申请人：NISSAN CHEMICAL INDUSTRIES LTD.

  公开号：EP0268892A2

  公开（公告）日：1988-06-01

  Substituted-amido derivatives, method for preparation of the same and phytopathogenic fungicides containing the same. Disclosed are substituted-amido derivatives of a general formula (I): in which A represents a 5-membered hetero-aromatic group as specifically defined herein; B represents a 5- membered hetero-aromatic group as specifically defined herein or represents a group of OR7 or SR7; D represents a cyano, thiocarbamoyl or acylthiocarbamoyl group of -CN, -CSNH2 or -CSNHCORs; and R7 and R8 each represent a group as specifically defiend herein, as well as a method for preparation of the said derivatives and a fungicide containing the said derivative as an active ingredient.

  取代-氨基衍生物、其制备方法和含有其的植物病原菌杀菌剂。本发明公开了通式(I)的取代-氨基衍生物： 其中 A 代表本文具体定义的 5 元杂芳族基团；B 代表本文具体定义的 5 元杂芳族基团或代表 OR7 或 SR7 的基团；D 代表-CN、-CSNH2 或-CSNHCORs 的氰基、硫代氨基甲酰基或酰基硫代氨基甲酰基；R7 和 R8 各代表本文具体定义的基团，以及上述衍生物的制备方法和含有上述衍生物作为活性成分的杀真菌剂。
• [EN] INSECTICIDAL COMPOUNDS BASED ON ARYLTHIOACETAMIDE DERIVATIVES<br/>[FR] COMPOSÉS INSECTICIDES À BASE DE DÉRIVÉS D'ARYLTHIOACÉTAMIDE
  申请人：SYNGENTA PARTICIPATIONS AG

  公开号：WO2014079935A9

  公开（公告）日：2014-09-04