9-(2,3-dichlorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 9-(2,3-dichlorophenyl)-2,6,7-trihydroxy-3H-xanthen-3-one
• 英文别名: 9-(2,3-dichlorophenyl)-2,6,7-trihydroxyxanthen-3-one
• 化学式: C₁₉H₁₀Cl₂O₅
• 分子量: 389.2
• InChiKey: BQORZESIOCMVDH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  26
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• COMPOSITIONS AND METHODS FOR INHIBITION OF HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET SIGNALING
  申请人：Bottaro Donald P.

  公开号：US20110281907A1

  公开（公告）日：2011-11-17

  Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met obtained by virtual screening, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives and analogs of c-Met inhibitors and methods of use thereof are provided. Formula (I)
• US8569360B2
  申请人：——

  公开号：US8569360B2

  公开（公告）日：2013-10-29
• [EN] COMPOSITIONS AND METHODS FOR INHIBITION OF HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET SIGNALING<br/>[FR] COMPOSITIONS ET PROCÉDÉS D'INHIBITION DE LA SIGNALISATION DE RÉCEPTEUR C-MET DE FACTEUR DE CROISSANCE D'HÉPATOCYTE
  申请人：US HEALTH

  公开号：WO2009124024A1

  公开（公告）日：2009-10-08

  Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met obtained by virtual screening, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives.and analogs of c-Met inhibitors and methods of use thereof are provided. Formula (I)