6-氨基-4-羟基萘-2-磺酸钠 | 16781-08-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 6-氨基-4-羟基萘-2-磺酸钠
• CAS: 16781-08-1
• 化学式: C10H9NNaO4S
• 分子量: 262.24
• InChiKey: OHLKVYOORZMISA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.99
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  109
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• PHARMACEUTICAL COMPOSITIONS CONTAINING SULPHONIC ACID DERIVATIVES
  申请人：Italfarmaco, S.A.

  公开号：EP1602644A1

  公开（公告）日：2005-12-07

  A naphthalenesulfonic acid or quinolinesulfonic acid of formula (I), wherein A is N or a CR8 formula group, where R8 is H, OH, NR10R11, independently from one another, where R10 and R11 represent H or C1-C6 alkyl or a group of formula NH-CO-R12, where R12 is C1-C6 alkyl or C6-C10 aryl; R1 and R2 represent H or SO3R9, independently from one another, where R9 is H, ammonium or a cation of an alkali or alkaline-earth metal; R3 is H or OH; and R4, R5, R6 and R7 represent H, an NR10R11 or NH-CO-R12 group, independently from one another; on the condition that (i) at least one of R1 or R2 is SO3R9, and (ii) at least one of R4, R5, R6 or R7 is an NR10R11 or NH-CO-R12 group, or their pharmaceutically acceptable salts; and a pharmaceutically acceptable excipient.

  一种具有化学式（I）的萘磺酸或喹啉磺酸，其中A为N或CR8配方基团，其中R8为H、OH、NR10R11，独立地，其中R10和R11分别代表H或C1-C6烷基或配方NH-CO-R12的基团，其中R12为C1-C6烷基或C6-C10芳基；R1和R2独立地代表H或SO3R9，其中R9为H、铵或碱金属或碱土金属的阳离子；R3为H或OH；R4、R5、R6和R7独立地代表H、NR10R11或NH-CO-R12基团；条件是（i）R1或R2中至少有一个为SO3R9，（ii）R4、R5、R6或R7中至少有一个为NR10R11或NH-CO-R12基团，或它们的药用可接受盐；以及药用可接受的赋形剂。
• Pharmaceutical compositions containing sulphonic acid derivatives
  申请人：Banfi Tosi María Beatriz

  公开号：US20060160849A1

  公开（公告）日：2006-07-20

  A naphthalenesulfonic acid or quinolinesulfonic acid of formula (I), wherein A is N or a CR 8 formula group, where R 8 is H, OH, NR 10 R 11 , independently from one another, where R 10 and R 11 represent H or C 1 -C 6 alkyl or a group of formula NH—CO—R 12 , where R 12 is C 1 -C 6 alkyl or C 6 -C 10 aryl; R 1 and R 2 represent H or SO 3 R 9 , independently from one another, where R 9 is H, ammonium or a cation of an alkali or alkaline-earth metal; R 3 is H or OH; and R 4 , R 5 , R 6 and R 7 represent H, an NR 10 R 11 or NH—CO—R 12 group, independently from one another; on the condition that (i) at least one of R 1 or R 2 is SO 3 R 9 , and (ii) at least one of R 4 , R 5 , R 6 or R 7 is an NR 10 R 11 or NH—CO—R 12 group, or their pharmaceutically acceptable salts; and a pharmaceutically acceptable excipient.

  公式（I）中的萘磺酸或喹啉磺酸，其中A为N或CR8配方基团，其中R8为H，OH，NR10R11，独立地，其中R10和R11代表H或C1-C6烷基或配方为NH-CO-R12的基团，其中R12为C1-C6烷基或C6-C10芳基；R1和R2独立地代表H或SO3R9，其中R9为H，铵离子或碱金属或碱土金属阳离子；R3代表H或OH；R4、R5、R6和R7独立地代表H，NR10R11或NH-CO-R12基团；条件是（i）R1或R2至少有一个为SO3R9，且（ii）R4、R5、R6或R7至少有一个为NR10R11或NH-CO-R12基团，或其药学上可接受的盐；以及药学上可接受的赋形剂。
• Cement admixture
  申请人：Kao Corporation

  公开号：EP0469625A2

  公开（公告）日：1992-02-05

  Cement and aggregates are mixed with each other by the use of a dispersant to the effect of water reduction and prevention of slump loss, the dispersant comprising (1) (I), (Ila) and an amine reaction terminator of (Ilb), (Ilc), (IVg) and/or (IVh) ; (2) (I), (Ilb) and/or (Ilc) and (Ille) and/or (Illf) ; or (3) (I), (Ila) and (Ille) and/or (Illf), in which formulae, R is hydrogen or an alkyl having 1 to 6 carbon atoms ; X is an alkali metal ; X1 is hydrogen, an alkyl having 1 to 6 carbon atoms, carboxylic group, an alkali metal salt carboxylate, sulfonic group, an alkali metal salt sulfonate, hydroxy or methoxy ; Y1 is carboxyic or an alkali metal salt carboxylate, sulfonic or an alkali metal salt sulfonate ; Y is hydrogen or an alkali metal ; Z is hydrogen, an alkyl having 1 to 6 carbon atoms or -CH2S03M ; and M is hydrogen or an alkali metal.

  通过使用分散剂将水泥和集料相互混合，以达到减水和防止坍落度损失的效果，分散剂包括 (1) (I)、(Ila) 和 (Ilb)、(Ilc)、(IVg) 和/或 (IVh) 的胺反应终止剂；(2) (I)、(Ilb)和/或(Ilc)和(Ille)和/或(Illf)；或 (3) (I)、(Ila)和(Ille)和/或(Illf)，在这些式中，R 是氢或具有 1 至 6 个碳原子的烷基；X 是碱金属；X1 是氢、具有 1 至 6 个碳原子的烷基、羧基、碱金属盐羧酸盐、磺酸基、碱金属盐磺酸盐、羟基或甲氧基；Y1 是羧基或碱金属盐羧酸盐、磺酸基或碱金属盐磺酸盐；Y 是氢或碱金属；Z 是氢、具有 1 至 6 个碳原子的烷基或-CH2S03M；M 是氢或碱金属。
• Process for the preparation of a functional group-containing polyarylene sulfide resin
  申请人：Tonen Chemical Corporation

  公开号：EP0900817A2

  公开（公告）日：1999-03-10

  A simple and convenient process is provided to introduce a sufficient quantity of functional groups to a main chain or terminals of the chain of a polyarylene sulfide resin to improve properties of the resin. The invention provides a process for heat oxidation crosslinking a polyarylene sulfide resin, characterized by conducting the heat oxidation crosslinking reaction in the presence of at least one organic compound having at least one active-hydrogen-containing group or at least one organic compound having at least one active-hydrogen-containing group and a group derived from an active hydrogen containing group by substituting an active hydrogen of the active hydrogen containing group with an alkali metal, to thereby prepare a functional group-containing polyarylene sulfide resin.

  本发明提供了一种简单方便的工艺，可在聚芳基硫醚树脂的主链或链的末端引入足够数量的官能团，以改善树脂的性能。 本发明提供了一种热氧化交联聚芳基硫醚树脂的工艺，其特征是在至少一种具有至少一个含活性氢基团的有机化合物或至少一种具有至少一个含活性氢基团的有机化合物和通过用碱金属取代活性含氢基团中的活性氢而衍生的基团的存在下进行热氧化交联反应，从而制备含官能团的聚芳基硫醚树脂。
• EP1994929A1
  申请人：——

  公开号：EP1994929A1

  公开（公告）日：2008-11-26