1-(5-hydroxy-indol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol | 70265-28-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢异喹啉
• 英文名称: 1-(5-hydroxy-indol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol
• 英文别名: 1-[(5-hydroxy-1H-indol-3-yl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
• CAS: 70265-28-0
• 化学式: C₁₈H₁₈N₂O₃
• 分子量: 310.353
• InChiKey: WKIIZNZWOQFDKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  88.5
• 氢给体数：
  5
• 氢受体数：
  4

文献信息

• [EN] BIOTRANSFORMATION REACTIONS<br/>[FR] RÉACTIONS DE BIOTRANSFORMATION
  申请人：COMMW SCIENT IND RES ORG

  公开号：WO2016065425A1

  公开（公告）日：2016-05-06

  The present disclosure relates to a method of preparing heteropolycyclic compounds. In some embodiments, the heteropolycyclic compounds are prepared by Pictet-Spengler reaction using a Pictet-Spenglerase biocatalyst and the aldehyde substrate for the Pictet- Spenglerase biocatalyst reaction is produced in situ by a transaminase biocatalyst. The use of the heteropolycyclic compounds is also described.