3-[4,5-Dichloro-2-[(1-propan-2-ylcyclohexanecarbonyl)amino]phenyl]-2,2-bis(methylsulfanyl)propanoic acid

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-[4,5-Dichloro-2-[(1-propan-2-ylcyclohexanecarbonyl)amino]phenyl]-2,2-bis(methylsulfanyl)propanoic acid
• 英文别名: 3-[4,5-dichloro-2-[(1-propan-2-ylcyclohexanecarbonyl)amino]phenyl]-2,2-bis(methylsulfanyl)propanoic acid
• 化学式: C₂₁H₂₉Cl₂NO₃S₂
• 分子量: 478.5
• InChiKey: BSRNKRNKSUTZGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  29
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION COMPRISING AN APOLIPOPROTEIN PEPTIDE/PHOSPHOLIPID COMPLEX
  申请人：Institut de Cardiologie de Montreal

  公开号：US20140309426A1

  公开（公告）日：2014-10-16

  The present invention features pharmaceutical compositions and methods of using pharmaceutical compositions for treating left ventricular diastolic dysfunction. In particular, the pharmaceutical compositions include an apolipoprotein complex comprising a lipid fraction and a protein fraction.
• METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS
  申请人：DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH

  公开号：US20190070178A1

  公开（公告）日：2019-03-07

  The invention provides compositions and methods useful for treating or preventing cardiovascular disorders and lowering risk of cardiovascular events.