Propyl 1,4-diazepane-1-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂卓
• 英文名称: Propyl 1,4-diazepane-1-carboxylate
• 英文别名: propyl 1,4-diazepane-1-carboxylate
• 化学式: C₉H₁₈N₂O₂
• 分子量: 186.25
• InChiKey: XILTXYJUJSGLPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  41.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Charged ion channel blockers and methods for use
  申请人：Nocion Therapeutics, Inc.

  公开号：US10968179B2

  公开（公告）日：2021-04-06

  The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.

  本发明提供了式（I）化合物或其药学上可接受的盐类： 本发明的化合物、组合物、方法和试剂盒可用于治疗疼痛、瘙痒和神经源性炎症。
• CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE
  申请人：Nocion Therapeutics, Inc.

  公开号：EP3938345A1

  公开（公告）日：2022-01-19
• Charged Ion Channel Blockers and Methods for Use
  申请人：Nocion Therapeutics, Inc.

  公开号：US20200290953A1

  公开（公告）日：2020-09-17

  The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.
• [EN] CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE<br/>[FR] BLOQUEURS DE CANAUX IONIQUES CHARGÉS ET PROCÉDÉS D'UTILISATION
  申请人：NOCION THERAPEUTICS INC

  公开号：WO2020185830A1

  公开（公告）日：2020-09-17

  The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof: (I) The compounds, compositions, methods and kits of the invention are useful for the treatment of pain, itch, and neurogenic inflammation.