1-methoxy-4-(1-methoxy-2-(4-(perfluorooctyl)phenyl)ethyl)-benzene | 1343512-51-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1-methoxy-4-(1-methoxy-2-(4-(perfluorooctyl)phenyl)ethyl)-benzene
• 英文别名: 1-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-Heptadecafluorooctyl)-4-[2-methoxy-2-(4-methoxyphenyl)ethyl]benzene；1-(1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctyl)-4-[2-methoxy-2-(4-methoxyphenyl)ethyl]benzene
• CAS: 1343512-51-5
• 化学式: C₂₄H₁₇F₁₇O₂
• 分子量: 660.371
• InChiKey: XROVXNXWSXTEJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.1
• 重原子数：
  43
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  19

反应信息

• 作为产物：
  描述：

  甲醇 、 4-甲氧基苯乙烯 、 4-(perfluorooctyl)benzenediazonium trifluoroacetate 在 di-μ-chlorobis[5-hydroxy-2-[1-(hydroxyimino)ethyl]phenyl]palladium(II) dimer 作用下， 反应 0.25h， 以60%的产率得到1-methoxy-4-(1-methoxy-2-(4-(perfluorooctyl)phenyl)ethyl)-benzene
  参考文献：
  名称：

  Fluorous aryl compounds by Matsuda–Heck reaction

  摘要：

  Fluorous aryl compounds are obtained through the arylation of different electron-rich and electron-poor olefins with an arenediazonium salt bearing a fully fluorinated octyl-ponytail at the para position. The Matsuda-Heck reactions are catalyzed by Pd(OAc)(2) or 4-hydroxyacetophenone oxime-derived palladacycle as efficient sources of Pd nanoparticles, with loadings of 1 mol % Pd, at room temperature, in methanol and without the need to add external base. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.09.046

文献信息

• Fluorous aryl compounds by Matsuda–Heck reaction
  作者：Jordi Salabert、Rosa María Sebastián、Adelina Vallribera、Anna Roglans、Carmen Nájera

  DOI：10.1016/j.tet.2011.09.046

  日期：2011.11

  Fluorous aryl compounds are obtained through the arylation of different electron-rich and electron-poor olefins with an arenediazonium salt bearing a fully fluorinated octyl-ponytail at the para position. The Matsuda-Heck reactions are catalyzed by Pd(OAc)(2) or 4-hydroxyacetophenone oxime-derived palladacycle as efficient sources of Pd nanoparticles, with loadings of 1 mol % Pd, at room temperature, in methanol and without the need to add external base. (C) 2011 Elsevier Ltd. All rights reserved.