3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-(pyridin-2-ylmethylsulfanyl)pyridazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• 英文名称: 3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-6-(pyridin-2-ylmethylsulfanyl)pyridazine
• 化学式: C₁₈H₁₅N₃O₂S
• 分子量: 337.4
• InChiKey: YXHVGWGMJYRDJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  82.4
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• COMPOUNDS COMPRISING LINKED HETEROARYL MOIETIES AND THEIR USE AS NOVEL UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS FOR COMESTIBLE COMPOSITIONS
  申请人：TACHDJIAN Catherine

  公开号：US20130071536A1

  公开（公告）日：2013-03-21

  The inventions disclosed herein relate to the discovery of the use of compounds having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly, savory (“umami”) taste modifiers, savory flavoring agents and savory flavor enhancers in foods, beverages, and other comestible compositions.

  本发明涉及以下化学式的化合物及其某些亚属或种类的发现，作为食品、饮料和其他可食用组合物中的风味或口味调节剂，特别是咸味（"鲜味"）调节剂、咸味调味剂和咸味增强剂。
• US8784782B2
  申请人：——

  公开号：US8784782B2

  公开（公告）日：2014-07-22
• US8968708B2
  申请人：——

  公开号：US8968708B2

  公开（公告）日：2015-03-03
• [EN] CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES<br/>[FR] THÉRAPIES BASÉES SUR UN LIGAND DE RÉCEPTEUR CHIMIOSENSORIEL
  申请人：ELCELYX THERAPEUTICS INC

  公开号：WO2012054526A2

  公开（公告）日：2012-04-26

  Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administering a composition comprising a chemosensory receptor ligand. Also provided herein are chemosensory receptor ligand compositions and methods for the preparation thereof for use in the methods of the present invention.