2-Methoxy-4-[2-(4-methylsulfonylphenyl)ethenyl]benzaldehyde

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2-Methoxy-4-[2-(4-methylsulfonylphenyl)ethenyl]benzaldehyde
• 英文别名: 2-methoxy-4-[2-(4-methylsulfonylphenyl)ethenyl]benzaldehyde
• 化学式: C₁₇H₁₆O₄S
• 分子量: 316.4
• InChiKey: ZGSAGMUALHYDLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  68.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• IMAGING OF MYELIN BASIC PROTEIN
  申请人：Siclovan Tiberiu Mircea

  公开号：US20100310456A1

  公开（公告）日：2010-12-09

  The present invention relates to methods for myelin basic protein detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the agent, and determining myelination in the subject by detecting binding to myelin basic protein. Methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using an agent with specific binding to myelin basic protein are also provided as is a kit containing the agent or its derivatives for use in detecting myelin basic protein

  本发明涉及用于髓鞘基础蛋白检测的方法，包括识别患有或被诊断为髓鞘相关神经病变风险的受试者，将药剂经肠外途径给予受试者，并通过检测与髓鞘基础蛋白的结合来确定受试者的髓鞘形成情况。还提供了用具有特异性结合髓鞘基础蛋白的药剂在样品中检测髓鞘及其局部浓度的定量测量方法，以及包含该药剂或其衍生物的试剂盒，用于检测髓鞘基础蛋白。
• [EN] IMAGING OF MYELIN BASIC PROTEIN<br/>[FR] IMAGERIE DE LA PROTÉINE BASIQUE DE LA MYÉLINE
  申请人：GEN ELECTRIC

  公开号：WO2010141704A2

  公开（公告）日：2010-12-09

  The present invention relates to methods for myelin basic protein detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the agent, and determining myelination in the subject by detecting binding to myelin basic protein. Methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using an agent with specific binding to myelin basic protein are also provided as is a kit containing the agent or its derivatives for use in detecting myelin basic protein.