N-(2-fluorophenyl)-N'-(2-ethoxybenzyl)piperazine | 353777-27-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: N-(2-fluorophenyl)-N'-(2-ethoxybenzyl)piperazine
• 英文别名: Piperazine, 1-[(2-ethoxyphenyl)methyl]-4-(2-fluorophenyl)-；1-[(2-ethoxyphenyl)methyl]-4-(2-fluorophenyl)piperazine
• CAS: 353777-27-2
• 化学式: C₁₉H₂₃FN₂O
• 分子量: 314.403
• InChiKey: VJTKGRVTQVCHRQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  15.7
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Methods and compositions comprising diamines as new anti-tubercular therapeutics
  申请人：Bogatcheva Elena

  公开号：US20050113574A1

  公开（公告）日：2005-05-26

  Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising novel diamine compositions for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.

  治疗传染性病原体引起的疾病，特别是结核病的方法和组合物。特别是提供了包含新型二胺组合物的用于治疗传染性疾病的方法和组合物。在一个实施方案中，这些方法和组合物用于治疗分枝杆菌感染，包括但不限于结核病。
• METHODS AND COMPOSITIONS COMPRISING DIAMINES AS NEW ANTI-TUBERCULAR THERAPEUTICS
  申请人：Sequella, Inc.

  公开号：EP1670314A2

  公开（公告）日：2006-06-21
• EP1670314A4
  申请人：——

  公开号：EP1670314A4

  公开（公告）日：2009-02-25
• US7884097B2
  申请人：——

  公开号：US7884097B2

  公开（公告）日：2011-02-08
• [EN] METHODS AND COMPOSITIONS COMPRISING DIAMINES AS NEW ANTI-TUBERCULAR THERAPEUTICS<br/>[FR] PROCEDES ET COMPOSITIONS RENFERMANT DES DIAMINES COMME NOUVEAUX PRODUITS THERAPEUTIQUES ANTITUBERCULEUX
  申请人：SEQUELLA INC

  公开号：WO2005034857A2

  公开（公告）日：2005-04-21

  Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising novel diamine compositions for the treatment of infectious diseases are provided. In one embodiment, these methods and compositions are used for the treatment of mycobacterial infections, including, but not limited to, tuberculosis.