4-Hydroxy-3-nitroso-2,7-naphthalenedisulfonic acid | 56548-44-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-Hydroxy-3-nitroso-2,7-naphthalenedisulfonic acid
• 英文别名: 4-hydroxy-3-nitrosonaphthalene-2,7-disulfonic acid
• CAS: 56548-44-8
• 化学式: C₁₀H₇NO₈S₂
• 分子量: 333.3
• InChiKey: OBKBNPNOIBVYQY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  175
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF
  申请人：Aires Pharmaceuticals, Inc.

  公开号：EP2237788A2

  公开（公告）日：2010-10-13
• AEROSOLIZED NITRITE AND NITRIC OXIDE -DONATING COMPOUNDS AND USES THEREOF
  申请人：Surber Mark W.

  公开号：US20090196930A1

  公开（公告）日：2009-08-06

  Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.
• AEROSOLIZED NITRITE AND NITRIC OXIDE-DONATING COMPOUNDS AND USES THEREOF
  申请人：AIRES PHARMACEUTICALS, INC.

  公开号：US20130028942A1

  公开（公告）日：2013-01-31

  Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.
• [EN] AEROSOLIZED NITRITE AND NITRIC OXIDE - DONATING COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS PERMETTANT D'OBTENIR DU NITRITE ET DE L'OXYDE NITRIQUE AÉROSOLISÉS ET LEURS UTILISATIONS
  申请人：AIRES PHARMACEUTICALS INC

  公开号：WO2009086470A2

  公开（公告）日：2009-07-09

  Disclosed herein are formulations of nitrite, nitrite salt, or nitrite- or nitric oxide-producing compounds suitable for aerosolization and use of such formulations for aerosol administration of nitrite, nitrite salt, or nitrite- or nitric oxide-donating compounds for the treatment of pulmonary arterial hypertension, intra-nasal or pulmonary bacterial infections, or to treat or prevent ischemic reperfusion injury of the heart, brain and organs involved in transplantation. In particular, inhaled nitrite, nitrite salt, or nitrite- or nitric oxide-donating compound specifically formulated and delivered to the respiratory tract for the indications is described. Compositions include all formulations, kits, and device combinations described herein. Methods include inhalation procedures and manufacturing processes for production and use of the compositions described.