Butyramide, N-2-naphthyl- | 69833-23-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Butyramide, N-2-naphthyl-
• 英文别名: N-naphthalen-2-ylbutanamide
• CAS: 69833-23-4
• 化学式: C₁₄H₁₅NO
• mdl: MFCD00033100
• 分子量: 213.27
• InChiKey: ZAKNXUSPSUTULS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.214
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE<br/>[FR] COMPOSÉS HÉTÉROARYLES À 5 CHAÎNONS CONTENANT UNE FRACTION HYDROXAMATE ET LEUR UTILISATION
  申请人：UNIV LILLE

  公开号：WO2020148403A1

  公开（公告）日：2020-07-23

  The present invention is directed to 5-membered heteroaryl compounds containing a hydroxamate moiety of Formula I, pharmaceutically acceptable salts or solvates thereof, and their use as sensitizers for chemotherapy of malignant tumors.

  本发明涉及含有Formula I的羟肟基团的5-成员杂芳化合物，其药用可接受盐或溶剂，以及它们作为恶性肿瘤化疗的增敏剂的用途。
• 5-MEMBERED HETEROARYL COMPOUNDS CONTAINING A HYDROXAMATE MOIETY AND THEIR USE
  申请人：Université de Lille

  公开号：EP3911645A1

  公开（公告）日：2021-11-24
• GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES
  申请人：BioMarin Pharmaceutical Inc.

  公开号：US20190263775A1

  公开（公告）日：2019-08-29

  Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).