1,1'-(Sulfonyldi-4,1-phenylene)bis(3-(1-naphthyl)urea)

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,1'-(Sulfonyldi-4,1-phenylene)bis(3-(1-naphthyl)urea)
• 英文别名: 1-naphthalen-1-yl-3-[4-[4-(naphthalen-1-ylcarbamoylamino)phenyl]sulfonylphenyl]urea
• 化学式: C₃₄H₂₆N₄O₄S
• 分子量: 586.7
• InChiKey: HAXMLCXHPFBIAC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.3
• 重原子数：
  43
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  125
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Cavity Induced Allosteric Modification Of Intermolecular Interactions And Methods Of Identifying Compounds That Effect The Same
  申请人：MURALI Ramachandran

  公开号：US20100151507A1

  公开（公告）日：2010-06-17

  Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Pharmaceutical composition comprising compounds that inhibit intermolecular interactions between a target protein and a modifier are disclosed. Methods of treating individual suffering from inflammatory conditions, undesirable immune responses, immunological conditions and bacterial infections are disclosed.
• US7653495B1
  申请人：——

  公开号：US7653495B1

  公开（公告）日：2010-01-26
• US8019557B2
  申请人：——

  公开号：US8019557B2

  公开（公告）日：2011-09-13
• US8785419B2
  申请人：——

  公开号：US8785419B2

  公开（公告）日：2014-07-22