Replaced CAS registry number(s): 64256-11-7 | 63710-10-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 蒽环类药物
• 英文名称: Replaced CAS registry number(s): 64256-11-7
• 英文别名: methyl (1R,2R,4S)-4-[5-[5-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate
• CAS: 63710-10-1
• 化学式: C₄₂H₅₅NO₁₇
• 分子量: 845.9
• InChiKey: VJRAUFKOOPNFIQ-XAYJNONASA-N

物化性质

• 熔点：
  146°C
• 沸点：
  771.16°C (rough estimate)
• 密度：
  1.2430 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  60
• 可旋转键数：
  10
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  261
• 氢给体数：
  7
• 氢受体数：
  18

文献信息

• Methods for Modulation of Acetyltransferase Activity and Applications Thereof Including Treatments
  申请人：The Board of Trustees of the Leland Stanford Junior University

  公开号：US20220196660A1

  公开（公告）日：2022-06-23

  Methods to identify modulators of histone acetyltransferases are described. Modulators of histone acetyltransferases can be used to treat individuals. In some instances, modulators of histone acetyltransferases are utilized to treat individuals having a neoplasm.
• [EN] METHODS FOR MODULATION OF ACETYLTRANSFERASE ACTIVITY AND APPLICATIONS THEREOF INCLUDING TREATMENTS<br/>[FR] MÉTHODES DE MODULATION DE L'ACTIVITÉ D'ACÉTYLTRANSFÉRASES ET APPLICATIONS ASSOCIÉES COMPRENANT DES TRAITEMENTS
  申请人：UNIV LELAND STANFORD JUNIOR

  公开号：WO2020219598A1

  公开（公告）日：2020-10-29

  Methods to identify modulators of histone acetyltransferases are described. Modulators of histone acetyltransferases can be used to treat individuals. In some instances, modulators of histone acetyltransferases are utilized to treat individuals having a neoplasm.