(+/-)-1.2-ditrityloxy-propanol-(3) | 120793-46-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: (+/-)-1.2-ditrityloxy-propanol-(3)
• 英文别名: (+/-)-3-Hydroxy-1.2-bis-triphenylmethoxy-propan；(+/-)-1.2-Bis-triphenylmethoxy-propanol-(3)；2,3-Ditrityloxypropan-1-ol
• CAS: 120793-46-6
• 化学式: C₄₁H₃₆O₃
• 分子量: 576.735
• InChiKey: RQZOXTNTNPJYRZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.7
• 重原子数：
  44
• 可旋转键数：
  12
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-stearoyloxy-2,3-bis-trityloxy-propane 在 sodium hydroxide 作用下， 生成 (+/-)-1.2-ditrityloxy-propanol-(3)
  参考文献：
  名称：

  Minimizing the Influence of Item Parameter Estimation Errors in Test Development: A Comparison of Three Selection Procedures

  摘要：

  In test development, item response theory (IRT) is a method to determine the amount of information that each item (i.e., item information function) and combination of items (i.e., test information function) provide in the estimation of an examinee's ability. Studies investigating the effects of item parameter estimation errors over a range of ability have demonstrated an overestimation of information when the most discriminating items are selected (i.e., item selection based on maximum information). In the present study, the authors examined the influence of item parameter estimation errors across 3 item selection methods-maximum no target, maximum target, and theta maximum-using the 2- and 3-parameter logistic IRT models. Tests created with the maximum no target and maximum target item selection procedures consistently overestimated the test information function. Conversely, tests created using the theta maximum item selection procedure yielded more consistent estimates of the test information function and, at times, underestimated the test information function. Implications for test development are discussed.

  DOI：

  10.1080/00220970109599488

文献信息

• NOVEL PROTECTING GROUPS AND USE THEREOF IN AN IMPROVED PROCESS FOR OLIGONUCLEOTIDE SYNTHESIS
  申请人：THE REGENTS OF THE UNIVERSITY OF COLORADO

  公开号：EP0775149B1

  公开（公告）日：2004-09-22
• US5889136A
  申请人：——

  公开号：US5889136A

  公开（公告）日：1999-03-30
• US6008400A
  申请人：——

  公开号：US6008400A

  公开（公告）日：1999-12-28
• Minimizing the Influence of Item Parameter Estimation Errors in Test Development: A Comparison of Three Selection Procedures
  作者：Mark J. Gierl、Dianne Henderson、Michael Jodoin、Don Klinger

  DOI：10.1080/00220970109599488

  日期：2001.1

  In test development, item response theory (IRT) is a method to determine the amount of information that each item (i.e., item information function) and combination of items (i.e., test information function) provide in the estimation of an examinee's ability. Studies investigating the effects of item parameter estimation errors over a range of ability have demonstrated an overestimation of information when the most discriminating items are selected (i.e., item selection based on maximum information). In the present study, the authors examined the influence of item parameter estimation errors across 3 item selection methods-maximum no target, maximum target, and theta maximum-using the 2- and 3-parameter logistic IRT models. Tests created with the maximum no target and maximum target item selection procedures consistently overestimated the test information function. Conversely, tests created using the theta maximum item selection procedure yielded more consistent estimates of the test information function and, at times, underestimated the test information function. Implications for test development are discussed.