(chloromethyl)dimethyl(3-(trimethylsilyl)propyl)silane | 17891-75-7

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: (chloromethyl)dimethyl(3-(trimethylsilyl)propyl)silane
• 英文别名: 1-(Chlormethyl-dimethyl-silyl)-3-trimethylsilyl-propan；1-Trimethylsilyl-3-(chlormethyl-dimethyl-silyl)-propan
• CAS: 17891-75-7
• 化学式: C₉H₂₃ClSi₂
• 分子量: 222.906
• InChiKey: IFNFQHMKHDTRKF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  12.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  (chloromethyl)dimethyl(3-(trimethylsilyl)propyl)silane 在 lithium 、 重水 作用下， 以 乙醚 为溶剂， 生成
  参考文献：
  名称：

  Asymmetric activation of dialkyl zirconocenes

  摘要：

  Asymmetric alkylmethyl zirconocene derivatives were readily synthesised from Cp(2)ZrCl(CH(3)), and the appropriate alkyllithium reagent. The alkyl groups contain a silyl functionality on the beta-position. These asymmetric dialkyl zirconocenes were successfully activated by B(C(6)F(5))(3), selectively abstracting the methyl group. The clear difference in the (13)C NMR resonances, due to the alkyl groups on the cationic zirconocene made it possible to conclude that selective activation of this class of compounds was possible. (C) 2010 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.06.011
• 作为产物：
  描述：

  氯甲基(二甲基)硅烷 、 烯丙基三甲基硅烷 在 铂 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 72.0h， 以87%的产率得到(chloromethyl)dimethyl(3-(trimethylsilyl)propyl)silane
  参考文献：
  名称：

  Chloromethylsilane functionalised dendrimers: synthesis and reactivity

  摘要：

  Tetraallylsilane was functionalised using (chloromethyl)dimethylsilane to give the first generation chloromethyl terminated dendrimer 1. The resulting dendrimer was successfully reacted with K[CpM(CO)(2)] (Cp = eta(5)-C5H5; M = Fe, Ru) to give Si[(CH2)(3)SiMe2CH2MCp(CO)(2)](4) functionalised dendrimers in satisfactory yield. Reaction of dendrimer 1 with NaI in acetone gave the -SiMe2CH2I functionalised dendrimer, while reactions of 1 with K[CpM(CO)(3)] (M = Mo, W, Re), Li[C5Me4H], Na[C5Me4H], the cobaloxime nucleophile or tert-BuLi were not successful. (C) 2004 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2003.11.034