N-(rhodamine-6G)lactam-N'-methacryloylethylenediamine | 1369774-25-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: N-(rhodamine-6G)lactam-N'-methacryloylethylenediamine
• 英文别名: N-[2-[3',6'-bis(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethyl]-2-methylprop-2-enamide
• CAS: 1369774-25-3
• 化学式: C₃₂H₃₆N₄O₃
• 分子量: 524.663
• InChiKey: ADSMMJGXDZQBNE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  39
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  82.7
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  甲基丙烯酰氯 、 N-(rhodamine-6G)lactam-ethylenediamine 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 以69.8%的产率得到N-(rhodamine-6G)lactam-N'-methacryloylethylenediamine
  参考文献：
  名称：

  混合聚合物胶束作为多功能可视热传感器，用于快速分析Al 3+和Fe 3+ †中的混合金属离子

  摘要：

  一种新的类型的响应混合双亲水性嵌段共聚物（DHBC）的多官能的基于视觉感温（与聚的混合共聚物（环氧乙烷） - b -聚（Ñ -isopropylacrylamide-共-2,4-甲基苯甲醛肟），（PEG - b -P（NIPAM-共-BDMa））和聚（环氧乙烷） - b -聚（ñ -isopropylacrylamide-共-Rhodamine 6G甲基丙烯酸）（PEG- b -P（NIPAM-共-Rh6GEMa））） ，用于检测Al 3+和Fe 3+是基于可逆加成-断裂链转移（RAFT）聚合设计和合成的。对传感过程的研究表明，该多功能视觉热传感器对Al 3+和Fe 3+离子具有比许多与环境有关的离子优良的选择性，并且具有纳摩尔级检测极限的高灵敏度。此外，多功能视觉热传感器可在温度升高时以（P（NIPAM- co -BDMa）/ P（NIPAM- co -Rh6GEMa））嵌段为核心，而溶

  DOI：

  10.1039/c8nj01917g

文献信息

• Multi-functional ratiometric fluorescent chemosensors of poly(N-isopropylacrylamide) containing rhodamine 6G and 1,8-naphthalimide moieties
  作者：Fan Kong、Mengqi Lin、Teng Qiu

  DOI：10.1016/j.polymer.2018.07.068

  日期：2018.8

  We have synthesized a multi-functional copolymer poly(N-isopropylacrylamide) (PNIPAM) containing rhodamine 6G and 1,8-naphthalimide moieties via reversible addition-fragmentation chain transfer (RAFT) radical polymerization. In a neutral condition, only an emission band with a peak at 520 nm is observed in the copolymer, which originates from 1,8-naphthalimide. The 520-nm photoluminescence (PL) intensity is markedly increased with decreasing the pH value of Britton-Robinson buffers, but changed instinctively by the concentration of Fe3+. The spirolactam ring-opening of the rhodamine 6G moiety is responsible for the PL changes of the copolymer in acidic conditions and Fe3+ aqueous solution, correspondingly, the 555-nm PL band of rhodamine 6G can be found for excitation at 400 nm. The PL intensity at 555 nm relative to that at 520 nm (I-555/I-520) is dependent on the resonance energy transfer from 1,8-naphthalimide to rhodamine 6G, which can be controlled by the chain conformations of the themoresponsive copolymer. The good linear relationships between the PL changes and the detection objects mean that the copolymer can be served as ratiometric chemosensors to probe pH, Fe3+ ions and temperature. (C) 2018 Elsevier Ltd. All rights reserved.
• Synthesis of an amphiphilic copolymer bearing rhodamine moieties and its self-assembly into micelles as chemosensors for Fe3+ in aqueous solution
  作者：Yu Wang、Haiqiang Wu、Jing Luo、Xiaoya Liu

  DOI：10.1016/j.reactfunctpolym.2011.12.007

  日期：2012.3

  We report on the fabrication of an amphiphilic random copolymer-based colorimetric and fluorescent chemosensor for Fe3+ ions that was prepared by free radical polymerization of a novel rhodamine-based Fe3+-recognizing monomer, R6GEM, with N-vinylpyrrolidone (NVP). Because of its amphiphilic property, the copolymer P(NVP-co-R6GEM) can self-assemble into micelles, which allows it to be used as a chemosensor in aqueous solution. Upon addition of Fe3+ ions to the micelle solution, visual color change and fluorescence enhancement were observed. Moreover, other metal ions did not induce obvious changes to the absorption and fluorescence spectra. The water dispersibility and biocompatibility of these polymer micelles could provide a new strategy for detecting analytes in environmental and biological systems. (C) 2011 Elsevier Ltd. All rights reserved.
• Mixed polymeric micelles as a multifunctional visual thermosensor for the rapid analysis of mixed metal ions with Al³⁺ and Fe³⁺
  作者：Juan Han、Yunfeng Cai、Yun Wang、Xiaohui Dai、Lei Wang、Chunmei Li、Baodong An、Liang Ni

  DOI：10.1039/c8nj01917g

  日期：——

  The detection limits using 0.05 g L−1 mixed micelles for the analysis of Al3+ and Fe3+ ions decreased from ∼5.95 to ∼4.02 nM, and ∼30.30 nM to ∼23.84 nM, respectively, upon changing the temperature from 25 °C to 40 °C. Furthermore, the mixed micelles in combination with Principal Component Analysis (PCA) and linear regression analysis to establish prediction models were used to achieve the successful

  一种新的类型的响应混合双亲水性嵌段共聚物（DHBC）的多官能的基于视觉感温（与聚的混合共聚物（环氧乙烷） - b -聚（Ñ -isopropylacrylamide-共-2,4-甲基苯甲醛肟），（PEG - b -P（NIPAM-共-BDMa））和聚（环氧乙烷） - b -聚（ñ -isopropylacrylamide-共-Rhodamine 6G甲基丙烯酸）（PEG- b -P（NIPAM-共-Rh6GEMa））） ，用于检测Al 3+和Fe 3+是基于可逆加成-断裂链转移（RAFT）聚合设计和合成的。对传感过程的研究表明，该多功能视觉热传感器对Al 3+和Fe 3+离子具有比许多与环境有关的离子优良的选择性，并且具有纳摩尔级检测极限的高灵敏度。此外，多功能视觉热传感器可在温度升高时以（P（NIPAM- co -BDMa）/ P（NIPAM- co -Rh6GEMa））嵌段为核心，而溶