4-[(1-Hydroxy-naphthalene-2-carbonyl)-amino]-3-nitro-benzenesulfonyl fluoride | 1868-64-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-[(1-Hydroxy-naphthalene-2-carbonyl)-amino]-3-nitro-benzenesulfonyl fluoride
• 英文别名: 4'-Fluorosulfonyl-1-hydroxy-2'-nitro-2-naphthanilide；4-[(1-hydroxynaphthalene-2-carbonyl)amino]-3-nitrobenzenesulfonyl fluoride
• CAS: 1868-64-0
• 化学式: C₁₇H₁₁FN₂O₆S
• 分子量: 390.349
• InChiKey: LYEFVXNLPOHNLG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  138
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• Cavity Induced Allosteric Modification Of Intermolecular Interactions And Methods Of Identifying Compounds That Effect The Same
  申请人：MURALI Ramachandran

  公开号：US20100151507A1

  公开（公告）日：2010-06-17

  Method of identifying compounds that modulate intermolecular interactions between a target protein and a modifier are disclosed. Pharmaceutical composition comprising compounds that inhibit intermolecular interactions between a target protein and a modifier are disclosed. Methods of treating individual suffering from inflammatory conditions, undesirable immune responses, immunological conditions and bacterial infections are disclosed.
• US7653495B1
  申请人：——

  公开号：US7653495B1

  公开（公告）日：2010-01-26
• US8019557B2
  申请人：——

  公开号：US8019557B2

  公开（公告）日：2011-09-13
• US8785419B2
  申请人：——

  公开号：US8785419B2

  公开（公告）日：2014-07-22