N-(1-萘基)-N-苯基丙烯酰胺 | 78820-11-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: N-(1-萘基)-N-苯基丙烯酰胺
• 中文别名: N-(1-萘基)-N-苯丙烯酰胺
• 英文名称: N-(1-Naphthyl)-N-phenylacrylamide
• 英文别名: N-naphthalen-1-yl-N-phenylprop-2-enamide
• CAS: 78820-11-8
• 化学式: C₁₉H₁₅NO
• 分子量: 273.3
• InChiKey: ZAAYATMUFGQSPN-UHFFFAOYSA-N

物化性质

• 熔点：
  102-113 °C (lit.)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• WGK Germany：
  3

文献信息

• Polymerizable, optically active polymer and process for preparing polymerizable polymer
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP0095086A1

  公开（公告）日：1983-11-30

  A polymerizable polymer is obtained by the anionic polymerization and termination by use of a vinyl monomer. It produces a graft copolymer by co-polymerization with another monomer. The process produces a new, polymerizable, optically active polymer and a graft copolymer thereof.

  一种可聚合聚合物是通过阴离子聚合并使用乙烯基单体终止而得到的。它通过与另一种单体共聚产生接枝共聚物。该工艺可生产出一种新的、可聚合的光学活性聚合物及其接枝共聚物。
• Methods, systems and apparatuses for testing and calibrating fluorescent scanners
  申请人：Affymetrix, Inc.

  公开号：US10422750B2

  公开（公告）日：2019-09-24

  Disclosed are calibration apparatuses for fluorescent microscopy instruments and methods of making and using them. Specifically, disclosed are calibration apparatuses with a fluorescent layer, such as photoresist, deposited on a substrate, with an optional layer of a reflective material, such as chrome. Illumination of the fluorescent and/or reflective layers, and detection and analysis of the resulting emissions allows evaluation of the instrument with respect to both reflective and fluorescent channels. Selection of appropriate fluorescent materials for the one or more fluorescent layers allows the evaluation of an instrument with respect to different fluorophores, as would be used with an instrument capable of two color detection. Inclusion of a reflective layer further allows the evaluation and calibration of all optical channels of an instrument, including the reflective channel and two or more fluorescent channels, with a single calibration apparatus for imaging criteria such as uniformity, contrast and emission signal strength.

  本发明公开了荧光显微仪器的校准装置及其制造和使用方法。具体而言，所公开的校准装置具有沉积在基板上的荧光层（如光刻胶），以及可选的反射材料层（如铬）。对荧光层和/或反射层进行照明，并对由此产生的辐射进行检测和分析，从而对仪器的反射通道和荧光通道进行评估。为一层或多层荧光层选择适当的荧光材料，可以对仪器进行不同荧光团的评估，就像对能够进行双色检测的仪器进行评估一样。加入反射层后，还可对仪器的所有光学通道（包括反射通道和两个或多个荧光通道）进行评估和校准，只需使用一个校准装置，即可达到成像标准，如均匀度、对比度和发射信号强度。
• Photoluminescent nanoparticles and their uses in detection or quantification of singlet oxygen
  申请人：Trustees of Tufts College

  公开号：US10675362B2

  公开（公告）日：2020-06-09

  A composition, as well as methods using the composition, for detection or quantification of a molecule at a singlet state (e.g., singlet oxygen). The composition includes one or more nanoparticles, and the nanoparticle has an energy donor, an energy acceptor associated with the energy donor, and an energy transfer mechanism between the energy donor and the energy acceptor.

  一种用于检测或量化单线态分子（如单线态氧）的组合物以及使用该组合物的方法。该组合物包括一个或多个纳米粒子，纳米粒子具有能量供体、与能量供体相关的能量受体以及能量供体与能量受体之间的能量转移机制。
• Responsive microgel and methods related thereto
  申请人：——

  公开号：US20030152623A1

  公开（公告）日：2003-08-14

  A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.

  本发明提供了一种响应型微凝胶，该微凝胶可对选自由温度、pH 值和离子条件组成的组中的一种或多种水性条件的变化作出体积上和可逆的响应、和离子条件）组成的共价交联均聚可离子化单体的可离子化网络，其中可离子化网络与两性共聚物共价连接，形成多条 "悬链"，两性共聚物的 "悬链 "在水溶液中形成不动的胶束状聚集体。还提供了一种响应性微凝胶，它包含至少一种治疗实体，并能在生理条件下提供治疗实体的线性和持续释放。
• PARTICLES COMPRISING AMPHIPHILIC COPOLYMERS, HAVING A CROSS-LINKED SHELL DOMAIN AND AN INTERIOR CORE DOMAIN, USEFUL FOR PHARMACEUTICAL AND OTHER APPLICATIONS
  申请人：G.D. Searle & Co.

  公开号：EP0907666A1

  公开（公告）日：1999-04-14