2-naphthoxy-triethylene glycol methacrylate | 1305339-09-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-naphthoxy-triethylene glycol methacrylate
• 英文别名: 2-[2-(2-Naphthalen-2-yloxyethoxy)ethoxy]ethyl 2-methylprop-2-enoate；2-[2-(2-naphthalen-2-yloxyethoxy)ethoxy]ethyl 2-methylprop-2-enoate
• CAS: 1305339-09-6
• 化学式: C₂₀H₂₄O₅
• 分子量: 344.408
• InChiKey: QSIQLVWTOWUKBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  25
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  54
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-(2-(2-(naphthalen-2-yloxy)ethoxy)ethoxy)ethanol 、 甲基丙烯酰氯 在 三乙胺 作用下， 以 乙醚 为溶剂， 以85%的产率得到2-naphthoxy-triethylene glycol methacrylate
  参考文献：
  名称：

  Supramolecular Glycopolymers in Water: A Reversible Route Toward Multivalent Carbohydrate–Lectin Conjugates Using Cucurbit[8]uril

  摘要：

  Supramolecular self-assembly and reversible switching has been demonstrated for the first time between monovalent and multivalent carbohydrate ligands and the multivalency effect on lectin binding has been investigated. The self-assembly process is mediated through noncovalent interactions between pendant moieties on a polymer scaffold and a monosaccharide-functionalized viologen with cucurbit-[8]uril (CB[8]) acting as a "supramolecular handcuff". The rate of binding of the tetrameric lectin Concanavalin A (Con A) to a mannose-containing supramolecular glycopolymer was investigated through a standard turbidimetric assay.

  DOI：

  10.1021/ma200343q

文献信息

• Supramolecular Glycopolymers in Water: A Reversible Route Toward Multivalent Carbohydrate–Lectin Conjugates Using Cucurbit[8]uril
  作者：Jin Geng、Frank Biedermann、Jameel M. Zayed、Feng Tian、Oren A. Scherman

  DOI：10.1021/ma200343q

  日期：2011.6.14

  Supramolecular self-assembly and reversible switching has been demonstrated for the first time between monovalent and multivalent carbohydrate ligands and the multivalency effect on lectin binding has been investigated. The self-assembly process is mediated through noncovalent interactions between pendant moieties on a polymer scaffold and a monosaccharide-functionalized viologen with cucurbit-[8]uril (CB[8]) acting as a "supramolecular handcuff". The rate of binding of the tetrameric lectin Concanavalin A (Con A) to a mannose-containing supramolecular glycopolymer was investigated through a standard turbidimetric assay.