2-thioxo-3-xanthen-9-yl-thiazolidin-4-one | 6319-51-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-thioxo-3-xanthen-9-yl-thiazolidin-4-one
• 英文别名: 2-Thioxo-3-xanthen-9-yl-thiazolidin-4-on；Thiazolidin-4-one, 3-(9H-xanthen-9-yl)-2-thioxo-；2-sulfanylidene-3-(9H-xanthen-9-yl)-1,3-thiazolidin-4-one
• CAS: 6319-51-3
• 化学式: C₁₆H₁₁NO₂S₂
• 分子量: 313.401
• InChiKey: HJXNREFULSQTKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  86.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  占吨醇 、 罗丹宁 生成 2-thioxo-3-xanthen-9-yl-thiazolidin-4-one
  参考文献：
  名称：

  Monti, Gazzetta Chimica Italiana, 1942, vol. 72, p. 515,518

  摘要：

  DOI：

文献信息

• Monti, Gazzetta Chimica Italiana, 1942, vol. 72, p. 515,518
  作者：Monti

  DOI：——

  日期：——
• OLIGONUCLEOTIDES LABELED WITH A PLURALITY OF FLUOROPHORES
  申请人：Allelogic Biosciences Corp.

  公开号：EP1689764A2

  公开（公告）日：2006-08-16
• DYE APPLICATION FOR CONFOCAL IMAGING OF CELLULAR MICROSTRUCTURE
  申请人：University of Utah Research Foundation

  公开号：EP2324362A1

  公开（公告）日：2011-05-25
• Oligonucleotides labeled with a plurality of fluorophores
  申请人：Mao Fei

  公开号：US20050272053A1

  公开（公告）日：2005-12-08

  An embodiment of the invention discloses new methods for designing labeled nucleic acid probes and primers by labeling oligonucleotides with a plurality of spectrally identical or similar dyes and optionally with one or more quencher dyes. Oligonucleotides labeled in accordance with some embodiments of the invention exhibit a detectable increase in signal, for example, fluorescent signal when the labeling dyes are separated from one another. Methods for separating the dye include cleaving the labeled oligonucleotides include using enzymes that have 5′-exonuclease activity. In one embodiment nucleic acid primers of the present invention may fluoresce upon hybridization to a target sequence and incorporation into the amplification product. Nucleic acid probes and primers of the present invention have wide applications ranging from general detection of a target nucleic acid sequence to clinical diagnostics. Major advantages of the oligonucleotides including nucleic acid probes and primers of many embodiments of the present invention are their synthetic simplicity, spectral versatility and superior fluorescent signal.
• US4232552A
  申请人：——

  公开号：US4232552A

  公开（公告）日：1980-11-11