N-(2-pyridin-2-ylethyl)-1H-indazole-3-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 英文名称: N-(2-pyridin-2-ylethyl)-1H-indazole-3-carboxamide
• 化学式: C₁₅H₁₄N₄O
• 分子量: 266.3
• InChiKey: AJUQLZXLHUJBQG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  70.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS FOR TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES
  申请人：Bristol-Myers Squibb Co.

  公开号：EP1254115A2

  公开（公告）日：2002-11-06
• [EN] CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS FOR TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES<br/>[FR] MODULATEURS DE RECEPTEURS AUX CANNABINOIDES, LEURS PROCEDES DE PREPARATION ET UTILISATIONS DE MODULATEURS DE RECEPTEURS AUX CANNABINOIDES POUR LE TRAITEMENT DE MALADIES RESPIRATOIRES ET NON RESPIRATOIRES
  申请人：BRISTOL MYERS SQUIBB CO

  公开号：WO2001058869A2

  公开（公告）日：2001-08-16

  Use of a compound for treating a respiratory disease in a mammal wherein the compound is a cannabinoid receptor modulator is disclosed. Compounds useful as cannabinoid receptor modulators for treating respiratory and non-respiratory leukocyte-activation associated diseases comprise compounds of formula (I), in which A and B are nitrogen or carbon, provided only one of A and B is nitrogen; and R1-R6 are as defined in the specification, wherein R2 with R5 may form a ring, and/or two R4 groups may form a six-membered aryl or heteroaryl ring, optionally having a substituent R6 forming a ring with R3.