4-(7-Acetyloxy-4-oxochromen-3-yl)oxybenzoic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 4-(7-Acetyloxy-4-oxochromen-3-yl)oxybenzoic acid
• 化学式: C₁₈H₁₂O₇
• 分子量: 340.3
• InChiKey: UXVMDBHRXJAIPW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  99.1
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• BENZOPYRAN DERIVATIVES AND USES THEREOF
  申请人：Novation Pharmaceuticals Inc.

  公开号：US20220016071A1

  公开（公告）日：2022-01-20

  The present disclosure provides for compounds useful for the treatment or prevention of disorders with an etiology associated with or comprising excessive cytokine or chemokine release. The compounds are also useful for the treatment of cancer, inflammatory disorders and disorders associated with an increased stability or translation of mRNA which has an mRNA instability sequence.
• [EN] BENZOPYRAN DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS DE BENZOPYRANE ET UTILISATIONS ASSOCIÉES
  申请人：NOVATION PHARMACEUTICALS INC

  公开号：WO2017027973A1

  公开（公告）日：2017-02-23

  The present disclosure provides for compounds useful for the treatment or prevention of disorders with an etiology associated with or comprising excessive cytokine or chemokine release. The compounds are also useful for the treatment of cancer, inflammatory disorders and disorders associated with an increased stability or translation of mRNA which has an mRNA instability sequence.