(Z)-[(4S,4aS,12aS)-4-(dimethylazaniumyl)-10,11,12a-trihydroxy-6-methyl-1,3,12-trioxo-4a,5-dihydro-4H-tetracen-2-ylidene]-aminomethanolate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 四环素类
• 英文名称: (Z)-[(4S,4aS,12aS)-4-(dimethylazaniumyl)-10,11,12a-trihydroxy-6-methyl-1,3,12-trioxo-4a,5-dihydro-4H-tetracen-2-ylidene]-aminomethanolate
• 化学式: C₂₂H₂₂N₂O₇
• 分子量: 426.4
• InChiKey: JGRMIMMCZBOWCW-LCGGBVFXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  31
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  161
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• Modified tet-inducible system for regulation of gene expression in plants
  申请人：Golovko Andrei

  公开号：US20050034187A1

  公开（公告）日：2005-02-10

  The present invention relates to modified tetracycline-inducible cassettes for controlling gene expression in organisms, particularly plants. Specifically, the invention provides novel tetracycline repressor and operator cassettes. The invention preferably provides a tetracycline-inducible expression cassette comprising both the tetracycline repressor and operator cassettes of the present invention wherein the repressor and operator cassettes are located on a single plasmid and/or vector. Also provided is a method of producing herbicide resistant plants using the modified tetracycline inducible cassettes of the present invention to control the expression of a herbicide resistance gene. Moreover, a method for identifying novel tetracycline analogs and/or functional equivalents using the modified tetracycline inducible cassettes of the present invention is also presented.

  本发明涉及用于控制生物，特别是植物基因表达的改良四环素诱导盒。具体地说，本发明提供了新型的四环素抑制剂和操作盒。本发明优选提供一种四环素诱导表达盒，该表达盒包括本发明的四环素抑制剂和操作者盒，其中抑制剂和操作者盒位于单个质粒和/或载体上。还提供了一种生产抗除草剂植物的方法，使用本发明的改良四环素诱导盒控制抗除草剂基因的表达。此外，还介绍了一种利用本发明的修饰四环素诱导盒鉴定新型四环素类似物和/或功能等效物的方法。
• MODIFIED i TET /i -INDUCIBLE SYSTEM FOR REGULATION OF GENE EXPRESSION IN PLANTS
  申请人：BASF Plant Science GmbH

  公开号：EP1322771A2

  公开（公告）日：2003-07-02
• [EN] MODIFIED TET-INDUCIBLE SYSTEM FOR REGULATION OF GENE EXPRESSION IN PLANTS<br/>[FR] SYSTEME INDUCTIBLE TET MODIFIE PERMETTANT LA REGULATION DE L'EXPRESSION GENIQUE DANS DES PLANTES
  申请人：BASF PLANT SCIENCE GMBH

  公开号：WO2002020811A2

  公开（公告）日：2002-03-14

  The present invention relates to modified tetracycline-inducible cassettes for controlling gene expression in organisms, particularly plants. Specifically, the invention provides novel tetracycline repressor and operator cassettes. The invention preferably provides a tetracycline-inducible expression cassette comprising both the tetracycline repressor and operator cassettes of the present invention wherein the repressor and operator cassettes are located on a single plasmid and/or vector. Also provided is a method of producing herbicide resistant plants using the modified tetracycline inducible cassettes of the present invention to control the expression of a herbicide resistance gene. Moreover, a method for identifying novel tetracycline analogs and/or functional equivalents using the modified tetracycline inducible cassettes of the present invention is also presented.