1-Fluoro-4-isopropylnaphthalin | 55830-93-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-Fluoro-4-isopropylnaphthalin
• 英文别名: 1-Fluoro-4-propan-2-ylnaphthalene
• CAS: 55830-93-8
• 化学式: C₁₃H₁₃F
• 分子量: 188.245
• InChiKey: YAYIAMUKFUBLIK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-氟-1-萘乙酮 生成 1-Fluoro-4-isopropylnaphthalin
  参考文献：
  名称：

  Substituent effects. XII. Substituent effects by fluorine-19 NMR

  摘要：

  DOI：

  10.1021/ja00841a034

文献信息

• [EN] HIGH TRIPLET YIELD PHENOTHIAZINE DONOR-ACCEPTOR COMPLEXES FOR PHOTOREDOX CATALYSIS<br/>[FR] COMPLEXES DONNEURS-ACCEPTEURS DE PHÉNOTHIAZINE À RENDEMENT TRIPLET ÉLEVÉ POUR CATALYSE PHOTOREDOX
  申请人：UNIV COLORADO REGENTS

  公开号：WO2021142287A1

  公开（公告）日：2021-07-15

  Phenothiazine compounds of Formula (I) are described herein. These compounds are useful as highly reducing organic photoredox catalysts. Suitable substrates for use with the compounds of Formula (I) include acrylates, styrene, acrylamides, acrylonitrile, vinyl chloride, methylacrylonitrile, vinyl acetate, and acrylic acid.

  本文描述了化学式（I）的吩噻嗪化合物。这些化合物可用作高度还原的有机光还原催化剂。适用于与化学式（I）的化合物一起使用的底物包括丙烯酸酯、苯乙烯、丙烯酰胺、丙烯腈、氯乙烯、甲基丙烯腈、乙酸乙烯酯和丙烯酸。
• ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES
  申请人：BEIJING SUMMER SPROUT TECHNOLOGY CO., LTD.

  公开号：US20220020935A1

  公开（公告）日：2022-01-20

  Disclosed are a novel organic electroluminescent material and a device thereof. Such a novel organic electroluminescent material has a structure of Formula 1, and when applied to the organic electroluminescent device, can improve the balance of electrons and holes in the organic electroluminescent device and thus bring excellent device effects such as the improvement of external quantum efficiency, current efficiency, and service life. The novel organic electroluminescent material can be used to prepare organic semiconductor devices and is suitable for different types of organic semiconductor devices, including but not limited to fluorescent OLEDs, phosphorescent OLEDs, white OLEDs, laminated OLEDs, OTFTs, OPVs, etc. Further disclosed are an electroluminescent device comprising the organic electroluminescent material and a compound formulation comprising the organic electroluminescent material.

  本发明涉及一种新型有机电致发光材料及其器件。所述新型有机电致发光材料具有一种化学结构式1，当应用于有机电致发光器件时，可以改善有机电致发光器件中电子和空穴的平衡，从而带来卓越的器件效果，如提高外部量子效率、电流效率和使用寿命。该新型有机电致发光材料可用于制备有机半导体器件，并适用于不同类型的有机半导体器件，包括但不限于荧光OLED、磷光OLED、白色OLED、层压OLED、OTFT、OPV等。进一步公开了包括所述有机电致发光材料和化合物配方的电致发光器件。
• PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS
  申请人：Gilead Sciences, Inc.

  公开号：US20180086719A1

  公开（公告）日：2018-03-29

  The present application provides the compounds of formula I or pharmaceutically acceptable salts, isomers, tautomer, or a mixture thereof, wherein t, R 1 , R 2 , R 3 , R 4 , and R 6 are as described herein.

  本申请提供了式I的化合物或其药学上可接受的盐、异构体、互变异构体或其混合物，其中t、R1、R2、R3、R4和R6如此处所述。
• SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND, THEIR PREPARATION AND USE IN MEDICAMENTS
  申请人：Mas Prio Josep

  公开号：US20090209528A1

  公开（公告）日：2009-08-20

  The present invention relates to substituted tetrahydroisoquinoline compounds of general formula (I), a process for their preparation, medicaments comprising said substituted tetrahydroisoquinoline compounds as well as the use of said substituted tetrahydroisoquinoline compounds for the preparation of medicaments, which are particularly suitable for the prophylaxis and/or treatment of disorders or diseases that are at least partially mediated via 5-HT 6 receptors.

  本发明涉及一般式(I)的取代四氢异喹啉化合物，其制备方法，包含所述取代四氢异喹啉化合物的药物以及利用所述取代四氢异喹啉化合物制备药物，特别适用于预防和/或治疗至少部分通过5-HT6受体介导的疾病或疾病的用途。
• Catalytic enantioselective synthesis of fluoromethylated stereocenters by asymmetric hydrogenation
  作者：Jianping Yang、Sudipta Ponra、Xingzhen Li、Bram B. C. Peters、Luca Massaro、Taigang Zhou、Pher G. Andersson

  DOI：10.1039/d2sc02685f

  日期：——

  an assortment of molecular recognition processes. Herein we report a catalytic method for the asymmetric synthesis of a variety of enantioenriched products bearing fluoromethylated stereocenters with excellent yields and enantioselectivities. Various N,P-ligands were designed and applied in the hydrogenation of fluoromethylated olefins and vinyl fluorides.

  氟甲基基团具有特定的空间和电子特性，并作为醇、硫醇、硝基和其他官能团的生物等排体，这在各种分子识别过程中非常重要。在此，我们报道了一种不对称合成各种带有氟甲基化立构中心的对映体富集产物的催化方法，具有优异的产率和对映选择性。设计了各种N,P-配体并将其应用于氟甲基化烯烃和氟乙烯的加氢。