sodium;2-[(2Z)-2-(6-nitro-2-oxo-4-sulfonaphthalen-1-ylidene)hydrazinyl]naphthalen-1-olate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: sodium;2-[(2Z)-2-(6-nitro-2-oxo-4-sulfonaphthalen-1-ylidene)hydrazinyl]naphthalen-1-olate
• 化学式: C20H12N3NaO7S
• 分子量: 461.4
• InChiKey: JHUJLRKQZAPSDP-GXTSIBQPSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.26
• 重原子数：
  32
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  173
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• Dry analytical element containing ampholyte
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0708335A2

  公开（公告）日：1996-04-24

  A dry analytical element comprising at least one water-permeable reagent layer and a porous spreading layer laminated in this order on a support, wherein at least one layer which is the water-permeable reagent layer, the porous spreading layer or an optional water-permeable layer contains a water-soluble polybasic amino carboxylic acid which is an ampholyte. By applying an analytical element of the invention, an analyte can be measured at a high sensitivity using a small amount of an enzyme, etc., and shelf file can be extended.

  一种干式分析元件，包括至少一层透水试剂层和一层多孔铺展层，依次层叠在一个支架上，其中至少有一层是透水试剂层、多孔铺展层或任选透水层，含有一种水溶性聚碱性氨基羧酸，它是一种两性离子。 通过应用本发明的分析元件，可以使用少量的酶等以高灵敏度测量分析物，并延长保质期。
• A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER
  申请人：Aqsens Health Oy

  公开号：EP3916391A1

  公开（公告）日：2021-12-01

  The present disclosure relates to a method for detecting a prostate cancer related biomarker, comprising contacting the diluted sample with a modulating agent selected from a group consisting of sodium;3-hydroxy-4-[(2-hydroxynaphthalen-1-yl)diazenyl]naphthalene-1-sulfonate, sodium;3-hydroxy-4-[(1-hydroxynaphthalen-2-yl)diazenyl]-7-nitronaphthalene-1-sulfonate, triisopropylsilane, and iron(III) chloride, and a luminescent label to obtain a measurement sample. Then, the measurement sample is incubated for a period of time and excited thereafter. Time-resolved luminescence signal of the label in the measurement sample is measured, leading to an increased likelihood of prostate cancer of the human subject if the luminescence signal is at least 50 % higher than for a control sample from a human subject without prostate cancer.

  本公开涉及一种检测前列腺癌相关生物标记物的方法，该方法包括将稀释样品与选自以下组别的调节剂接触3-羟基-4-[(2-羟基萘-1-基)偶氮]萘-1-磺酸钠、3-羟基-4-[(1-羟基萘-2-基)偶氮]-7-硝基萘-1-磺酸钠、三异丙基硅烷和氯化铁(III)以及发光标签组成的组中的调节剂接触，以获得测量样品。然后，将测量样品培养一段时间并激发。测量样品中标签的时间分辨发光信号，如果发光信号比没有前列腺癌的人体对照样品至少高出 50%，则人体患前列腺癌的可能性增加。
• Methods for coating surfaces with antimicrobial agents
  申请人：The Board of Regents of the University of Texas System

  公开号：US10589003B2

  公开（公告）日：2020-03-17

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.

  本发明公开了用抗菌剂涂覆或浸渍表面的方法，包括用包括抗菌剂和溶剂的组合物接触表面，并通过加热固化表面。还公开了降低需要使用医疗器械的受试者发生或恶化感染风险的方法，包括用抗菌剂涂覆或浸渍医疗器械表面，然后通过加热固化表面，从而降低发生或恶化感染的风险。
• Joint compounds and plasters with a complexometric dye and methods
  申请人：United States Gypsum Company

  公开号：US11236234B2

  公开（公告）日：2022-02-01

  A building construction product comprising an ionochromic dye, wherein the building construction product has a first color when the product comprises water, wherein the first color is dependent on the presence of metal ions in solution in the product; and wherein the product has a second color when the product has solidified. Methods of monitoring setting and drying reactions of building construction products, including setting-type and drying-type joint compounds and plasters.

  一种包含离子变色染料的建筑施工产品，其中，当产品包含水时，建筑施工产品具有第一种颜色，其中，第一种颜色取决于产品中溶液中金属离子的存在；当产品凝固时，产品具有第二种颜色。监测建筑产品凝固和干燥反应的方法，包括凝固型和干燥型接缝化合物和抹灰。
• Method of preparing integral multilayer analytical element
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP0254202B1

  公开（公告）日：1991-09-18