(2Z,4S,4aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 四环素类
• 英文名称: (2Z,4S,4aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione
• 化学式: C₂₂H₂₄N₂O₈
• 分子量: 444.4
• InChiKey: JYHCQVWYCGHXGP-JBOJHEFWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  32
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  182
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• COMBINATION OF IMMUNOMODULATOR AND ANTI-PATHOGENIC AGENT
  申请人：Nunes, Iseu Da Silva

  公开号：EP2259799B1

  公开（公告）日：2014-03-12
• Combination of Immunomodulator and Anti-Pathogenic Agent
  申请人：Nunes Iseu da Silva

  公开号：US20110028385A1

  公开（公告）日：2011-02-03

  A compound comprising combination of an immunomodulator and to at least one anti-pathogenic agent for treating of facultative or strict infections caused by intracellular microorganisms, the components of the combination or association of substances of the invention, the immunomodulator (proteic aggregate of ammonium and magnesium phospholinoleate-palmitoleate anhydride) and at least one substance with antimicrobial properties can be administered either jointly, simultaneously, consecutively or sequentially, in an appropriate form, according to their chemical properties, and in a dose effective against microorganisms in human and animals.
• US8889153B2
  申请人：——

  公开号：US8889153B2

  公开（公告）日：2014-11-18