[(Z)-(2,4-dioxochromen-3-ylidene)methyl]thiourea

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: [(Z)-(2,4-dioxochromen-3-ylidene)methyl]thiourea
• 化学式: C₁₁H₈N₂O₃S
• 分子量: 248.26
• InChiKey: NOUVJLNQHJVJIK-ALCCZGGFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  114
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Honokiol Derivates For the Treatment of Proliferative Disorders
  申请人：Arbiser Jack L.

  公开号：US20080300298A1

  公开（公告）日：2008-12-04

  The present invention provides novel honokiol derivatives, as well as pharmaceutical compositions containing the honokiol derivatives. These compounds and pharmaceutical compositions can be used in the prevention and/or treatment of cancer. In particular, honokiol derivatives, pharmaceutical compositions comprising the derivatives, and methods for their use in the treatment of myeloma are provided.