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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 三唑并嘧啶类

    三唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-benzofuran-2-yl-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H17F2N5O2
    1-benzofuran-2-yl-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-3-ylmethanone —— C17H16F2N6O
    [(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-3-ylmethanone
    —— 1-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)ethanone —— C19H18F3N5O2
    1-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)ethanone
    —— [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone —— C16H19F2N5O2
    [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(2R)-oxolan-2-yl]methanone
    —— (5S,7R)-5-[1-[2-(4-methylphenoxy)ethyl]piperidin-4-yl]-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine —— C20H26F3N5O
    (5S,7R)-5-[1-[2-(4-methylphenoxy)ethyl]piperidin-4-yl]-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidine
    —— 1-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-[[(2R)-oxan-2-yl]methoxy]ethanone —— C19H29F2N5O3
    1-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-[[(2R)-oxan-2-yl]methoxy]ethanone
    —— 1-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-phenylpropan-1-one —— C20H25F2N5O
    1-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-phenylpropan-1-one
    —— [(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-2-ylmethanone —— C17H16F2N6O
    [(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-2-ylmethanone
    —— cyclopentyl-[4-[(5S,7R)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C17H24F3N5O
    cyclopentyl-[4-[(5S,7R)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone —— C17H21F2N5OS
    [4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone
    —— 2-[(2S)-oxolan-2-yl]-1-[4-[(5S,7R)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C17H24F3N5O2
    2-[(2S)-oxolan-2-yl]-1-[4-[(5S,7R)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(3R)-1,1-dioxothiolan-3-yl]methanone —— C16H19F2N5O3S
    [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(3R)-1,1-dioxothiolan-3-yl]methanone
    —— cyclohexyl-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H27F2N5O
    cyclohexyl-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— cyclopentyl-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C17H25F2N5O
    cyclopentyl-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 1-[(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-thiophen-3-ylethanone —— C17H17F2N5OS
    1-[(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-thiophen-3-ylethanone
    —— [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(3S)-1,1-dioxothiolan-3-yl]methanone —— C16H19F2N5O3S
    [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(3S)-1,1-dioxothiolan-3-yl]methanone
    —— 1-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methoxyethanone —— C14H21F2N5O2
    1-[4-[(5S,7R)-7-(difluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methoxyethanone
    —— [(1R,6S)-7-bicyclo[4.1.0]heptanyl]-[4-[(5S,7R)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C19H26F3N5O
    [(1R,6S)-7-bicyclo[4.1.0]heptanyl]-[4-[(5S,7R)-7-(trifluoromethyl)-4,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— cyclohexyl-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H23F2N5O
    cyclohexyl-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 3-[[(3R)-1-(cyclopentanecarbonyl)piperidin-3-yl]methyl]-5-methyl-2H-triazolo[4,5-d]pyrimidin-7-one —— C17H24N6O2
    3-[[(3R)-1-(cyclopentanecarbonyl)piperidin-3-yl]methyl]-5-methyl-2H-triazolo[4,5-d]pyrimidin-7-one
    —— 3-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]methyl]-5-methyl-2H-triazolo[4,5-d]pyrimidin-7-one —— C15H20N6O2
    3-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]methyl]-5-methyl-2H-triazolo[4,5-d]pyrimidin-7-one
    —— 7-(difluoromethyl)-5-[(3S)-1-[(E)-3-(2-methoxyphenyl)prop-2-enyl]piperidin-3-yl]-[1,2,4]triazolo[1,5-a]pyrimidine —— C21H23F2N5O
    7-(difluoromethyl)-5-[(3S)-1-[(E)-3-(2-methoxyphenyl)prop-2-enyl]piperidin-3-yl]-[1,2,4]triazolo[1,5-a]pyrimidine
    —— 3-[[(3S)-1-(cyclobutanecarbonyl)piperidin-3-yl]methyl]-5-methyl-2H-triazolo[4,5-d]pyrimidin-7-one —— C16H22N6O2
    3-[[(3S)-1-(cyclobutanecarbonyl)piperidin-3-yl]methyl]-5-methyl-2H-triazolo[4,5-d]pyrimidin-7-one
    —— 5-methyl-3-[[(2R)-1-(thiophene-2-carbonyl)pyrrolidin-2-yl]methyl]-2H-triazolo[4,5-d]pyrimidin-7-one —— C15H16N6O2S
    5-methyl-3-[[(2R)-1-(thiophene-2-carbonyl)pyrrolidin-2-yl]methyl]-2H-triazolo[4,5-d]pyrimidin-7-one
    —— [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methoxythiophen-2-yl)methanone —— C17H17F2N5O2S
    [(3R)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methoxythiophen-2-yl)methanone
    —— 7-(difluoromethyl)-5-[(3R)-1-[(E)-3-(2-methoxyphenyl)prop-2-enyl]piperidin-3-yl]-[1,2,4]triazolo[1,5-a]pyrimidine —— C21H23F2N5O
    7-(difluoromethyl)-5-[(3R)-1-[(E)-3-(2-methoxyphenyl)prop-2-enyl]piperidin-3-yl]-[1,2,4]triazolo[1,5-a]pyrimidine
    —— 2-(5,7-dimethyl-2-methylsulfanyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-[(R)-phenyl(thiophen-2-yl)methyl]acetamide —— C21H21N5OS2
    2-(5,7-dimethyl-2-methylsulfanyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-N-[(R)-phenyl(thiophen-2-yl)methyl]acetamide
    —— N-[(1S)-1-(11,12-dimethyl-10-oxa-3,5,6,8-tetrazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl)ethyl]-2-ethoxyacetamide —— C15H19N5O3
    N-[(1S)-1-(11,12-dimethyl-10-oxa-3,5,6,8-tetrazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-4-yl)ethyl]-2-ethoxyacetamide
    —— thiophen-2-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C16H14F3N5OS
    thiophen-2-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 1,3-thiazol-4-yl-[(3S)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C15H13F3N6OS
    1,3-thiazol-4-yl-[(3S)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— furan-2-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C16H14F3N5O2
    furan-2-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 1,3-thiazol-4-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C15H13F3N6OS
    1,3-thiazol-4-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (4-methyl-1,3-thiazol-5-yl)-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C16H15F3N6OS
    (4-methyl-1,3-thiazol-5-yl)-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (2R)-1-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methyl-3-thiophen-2-ylpropan-1-one —— C19H21F2N5OS
    (2R)-1-[(3S)-3-[7-(difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methyl-3-thiophen-2-ylpropan-1-one
    —— 5-[1-[(3R)-3-phenylbutyl]piperidin-4-yl]-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine —— C21H24F3N5
    5-[1-[(3R)-3-phenylbutyl]piperidin-4-yl]-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine
    —— (3S)-5,5-dimethyl-3-[2-oxo-2-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethyl]oxolan-2-one —— C19H22F3N5O3
    (3S)-5,5-dimethyl-3-[2-oxo-2-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethyl]oxolan-2-one
    —— 1-[4-[7-(Difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methylpropan-1-one —— C15H19F2N5O
    1-[4-[7-(Difluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methylpropan-1-one
    —— 2-(1,3-Benzodioxol-5-yl)-1-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C20H18F3N5O3
    2-(1,3-Benzodioxol-5-yl)-1-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— (2S)-2-(3-methoxyphenoxy)-1-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C21H22F3N5O3
    (2S)-2-(3-methoxyphenoxy)-1-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— Cyclohexyl-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H22F3N5O
    Cyclohexyl-[4-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— cyclohexyl-[(3R)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H26F3N5O
    cyclohexyl-[(3R)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (2R)-2-methyl-3-thiophen-2-yl-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C19H24F3N5OS
    (2R)-2-methyl-3-thiophen-2-yl-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2R)-2-(2-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C20H23F4N5O2
    (2R)-2-(2-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (2S)-2-methyl-3-thiophen-2-yl-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C19H24F3N5OS
    (2S)-2-methyl-3-thiophen-2-yl-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (4,5-dimethylthiophen-3-yl)-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C18H22F3N5OS
    (4,5-dimethylthiophen-3-yl)-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (2S)-2-(2-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C20H23F4N5O2
    (2S)-2-(2-fluorophenoxy)-1-[(3S)-3-[(5S,7R)-7-(trifluoromethyl)-1,5,6,7-tetrahydro-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (4-chloro-1H-pyrazol-5-yl)-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C15H13ClF3N7O
    (4-chloro-1H-pyrazol-5-yl)-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 3-imidazol-1-yl-1-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C17H18F3N7O
    3-imidazol-1-yl-1-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— 1H-pyrazol-5-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C15H14F3N7O
    1H-pyrazol-5-yl-[(3R)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 1H-pyrazol-5-yl-[(3S)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C15H14F3N7O
    1H-pyrazol-5-yl-[(3S)-3-[7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone