(1S,2R,3S,4S)-[(2-(benzyloxy)-4-(2-(methoxy)ethoxymethoxy)-3-(trityloxymethyl))cyclopentyloxy]tert-butyldimethylsilane | 1169647-96-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: (1S,2R,3S,4S)-[(2-(benzyloxy)-4-(2-(methoxy)ethoxymethoxy)-3-(trityloxymethyl))cyclopentyloxy]tert-butyldimethylsilane
• CAS: 1169647-96-4
• 化学式: C₄₂H₅₄O₆Si
• 分子量: 682.973
• InChiKey: GROUARHPVKCVSM-IJERZTCISA-N

反应信息

• 作为反应物：
  描述：

  (1S,2R,3S,4S)-[(2-(benzyloxy)-4-(2-(methoxy)ethoxymethoxy)-3-(trityloxymethyl))cyclopentyloxy]tert-butyldimethylsilane 在 四丁基氟化铵 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以99%的产率得到(1S,2R,3S,4S)-[2-(benzyloxy)-4-(2-(methoxy)ethoxymethoxy)-3-(trityloxymethyl)]cyclopentanol
  参考文献：
  名称：

  An enantioselective synthesis of carbafuranose sugars based on a linchpin carbacyclisation approach

  摘要：

  Enantiopure carbafuranose derivatives were synthesised via a linchpin carbacyclisation process starting from 1,4-bisepoxides. Both 2-deoxy and 2-deoxy-6-hydroxycarbafuranose derivatives were obtained, which were converted to suitably protected precursors for carbanucleoside synthesis. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.02.019
• 作为产物：
  描述：

  2-甲氧基乙氧基甲基氯 、 (1S,2S,3R,4S)-[3-benzyloxy-4-(tertbutyldimethylsilyloxy)-2-(trityloxymethyl)]cyclopentanol 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 以92%的产率得到(1S,2R,3S,4S)-[(2-(benzyloxy)-4-(2-(methoxy)ethoxymethoxy)-3-(trityloxymethyl))cyclopentyloxy]tert-butyldimethylsilane
  参考文献：
  名称：

  An enantioselective synthesis of carbafuranose sugars based on a linchpin carbacyclisation approach

  摘要：

  Enantiopure carbafuranose derivatives were synthesised via a linchpin carbacyclisation process starting from 1,4-bisepoxides. Both 2-deoxy and 2-deoxy-6-hydroxycarbafuranose derivatives were obtained, which were converted to suitably protected precursors for carbanucleoside synthesis. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2009.02.019