{(1S,2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-(3S,5S)-3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-non-1-enyl]-5-triethylsilanyloxy-cyclopentyl}-methanol 在
正丁基锂 、 molecular sieve 、
pyridinium chlorochromate 作用下,
以
二氯甲烷 为溶剂,
反应 3.0h,
生成 7-{(1S,2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-(3S,5S)-3-(tert-butyl-dimethyl-silanyloxy)-5-methyl-non-1-enyl]-5-triethylsilanyloxy-cyclopentyl}-7-hydroxy-hept-5-ynoic acid