2-methyl-6-piperidino-hexan-2-ol | 108846-75-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2-methyl-6-piperidino-hexan-2-ol
• 英文别名: 2-Methyl-6-piperidin-1-ylhexan-2-ol
• CAS: 108846-75-9
• 化学式: C₁₂H₂₅NO
• 分子量: 199.337
• InChiKey: LZRGVXGQMPDIEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 铂 作用下， 生成 2-methyl-6-piperidino-hexan-2-ol
  参考文献：
  名称：

  Wartanjan; Badanjan, Izvestiya Akademii Nauk Armyanskoi SSR, Khimicheskie Nauki, 1959, vol. 12, p. 37,38,40

  摘要：

  DOI：

文献信息

• Lipid membrane structure for delivery into siRNA cell
  申请人：NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

  公开号：US11517528B2

  公开（公告）日：2022-12-06

  A lipid membrane structure includes, as lipid components, a lipid compound represented by Formula (I): (R 1 )(R 2 )C(OH)—(CH 3 ) a —(O—CO) b —X  (I) [in the formula, a represents an integer of 3 to 5; b represents an integer of 0 or 1; R 1 and R 2 each independently represents a linear hydrocarbon group that may have —CO—O—; and X represents a 5- to 7-membered non-aromatic heterocyclic group or a group represented by Formula (B) (in the formula, d represents an integer of 0 to 3, and R 3 and R 4 each independently represents a C 1-4 alkyl group or a C 2-4 alkenyl group, where, R 3 and R 4 may be bonded to each other to form a 5- to 7-membered non-aromatic heterocycle (where, one or two C 1-4 alkyl groups or C 2-4 alkenyl groups may be substituted on the ring)].

  一种脂质膜结构包括以下脂质成分：由式（I）表示的脂质化合物：(R1)(R2)C(OH)—(CH3)a—(O—CO)b—X  (I)[在该式中，a表示3至5的整数；b表示0或1的整数；R1和R2各自独立地表示一个线性碳氢基团，可能具有—CO—O—；X表示一个5至7个成员的非芳香杂环基团或由式（B）表示的基团（在该式中，d表示0至3的整数，R3和R4各自独立地表示一个C1-4烷基基团或C2-4烯基基团，其中，R3和R4可以连接在一起形成一个5至7个成员的非芳香杂环（其中，环上可能有一个或两个C1-4烷基基团或C2-4烯基基团被取代）]。
• LIPID MEMBRANE STRUCTURE FOR DELIVERY INTO siRNA CELL
  申请人：NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY

  公开号：US20200129431A1

  公开（公告）日：2020-04-30

  A lipid membrane structure includes, as lipid components, a lipid compound represented by Formula (I): (R 1 )(R 2 )C(OH)—(CH 3 ) a —(O—CO) b —X  (I) [in the formula, a represents an integer of 3 to 5; b represents an integer of 0 or 1; R 1 and R 2 each independently represents a linear hydrocarbon group that may have —CO—O—; and X represents a 5- to 7-membered non-aromatic heterocyclic group or a group represented by Formula (B) (in the formula, d represents an integer of 0 to 3, and R 3 and R 4 each independently represents a C 1-4 alkyl group or a C 2-4 alkenyl group, where, R 3 and R 4 may be bonded to each other to form a 5- to 7-membered non-aromatic heterocycle (where, one or two C 1-4 alkyl groups or C 2-4 alkenyl groups may be substituted on the ring)].