3'-(1-丁基磷酰)腺苷 | 52278-63-4

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 核糖核苷3'-磷酸盐
• 中文名称: 3'-(1-丁基磷酰)腺苷
• 中文别名: 3-(3,4-二氟苯基)苯甲酸
• 英文名称: 3'-(1-Butylphosphoryl)adenosine
• 英文别名: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] butyl hydrogen phosphate
• CAS: 52278-63-4
• 化学式: C₁₄H₂₂N₅O₇P
• 分子量: 403.33
• InChiKey: RVVKQBUWQFREIE-IDTAVKCVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  175
• 氢给体数：
  4
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  N-[9-[(3aR,4R,6R,6aR)-2-butoxy-6-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]purin-6-yl]benzamide 生成 3'-(1-丁基磷酰)腺苷
  参考文献：
  名称：

  KVASYUK, E. I.;KULAK, T. I.;ZAJTSEVA, G. V.;TKACHENKO, O. V.;MIXAJLOPULO,+, KOMPONENTY NUKLEIN. KISLOT: 8 BCEC. SIMP. PO TSELENAPRAVL. IZYSKANIYU LEK+

  摘要：

  DOI：

文献信息

• KVASYUK, E. I.;KULAK, T. I.;ZAJTSEVA, G. V.;TKACHENKO, O. V.;MIXAJLOPULO,+, ZH. ORGAN. XIMII, 26,(1990) N, S. 1229-1236
  作者：KVASYUK, E. I.、KULAK, T. I.、ZAJTSEVA, G. V.、TKACHENKO, O. V.、MIXAJLOPULO,+

  DOI：——

  日期：——
• KVASYUK, E. I.;KULAK, T. I.;ZAJTSEVA, G. V.;TKACHENKO, O. V.;MIXAJLOPULO,+, KOMPONENTY NUKLEIN. KISLOT: 8 BCEC. SIMP. PO TSELENAPRAVL. IZYSKANIYU LEK+
  作者：KVASYUK, E. I.、KULAK, T. I.、ZAJTSEVA, G. V.、TKACHENKO, O. V.、MIXAJLOPULO,+

  DOI：——

  日期：——
• JPS6160696A
  申请人：——

  公开号：JPS6160696A

  公开（公告）日：1986-03-28
• ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE
  申请人：Kett Warren Charles

  公开号：US20110190233A1

  公开（公告）日：2011-08-04

  The invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs). The invention also relates to processes for the preparation of the conjugates. Such conjugates are useful in the prophylaxis and/or treatment of disease conditions and in particular chronic disease conditions such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites.
• Anionic Conjugates of Glycosylated Bacterial Metabolite
  申请人：GLYCAN BIOSCIENCES LLC

  公开号：US20140323422A1

  公开（公告）日：2014-10-30

  The invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs). The invention also relates to processes for the preparation of the conjugates. Such conjugates are useful in the prophylaxis and/or treatment of disease conditions and in particular chronic disease conditions such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites.