2,4-Dianilino-6-methyl-1,3,5-triazin | 2039-34-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2,4-Dianilino-6-methyl-1,3,5-triazin
• 英文别名: 2-Methyl-4.6-dianilino-s-triazin；6-methyl-N,N'-diphenyl-[1,3,5]triazine-2,4-diamine；6-methyl-2-N,4-N-diphenyl-1,3,5-triazine-2,4-diamine
• CAS: 2039-34-1
• 化学式: C₁₆H₁₅N₅
• 分子量: 277.329
• InChiKey: JTGSWJBQPDXQGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  62.7
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,4-Dianilino-6-methyl-1,3,5-triazin 、 苯甲醇 在 ruthenium trichloride 、 potassium tert-butylate 作用下， 以 1,4-二氧六环 为溶剂， 反应 17.0h， 以98%的产率得到(E)-N²,N⁴-diphenyl-6-styryl-1,3,5-triazine-2,4-diamine
  参考文献：
  名称：

  钌催化1,3,5-三嗪甲基与醇的发散烷基化和烯烃化

  摘要：

  通过选择钌催化剂，已开发出可控制的烷基1,3,5-三嗪甲基与醇的烷基化或烯烃化反应。这种方法在克级反应中的成功应用表明它具有大量合成的潜力。

  DOI：

  10.1002/ejoc.202000781

文献信息

• Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups
  申请人：Candau Didier

  公开号：US20100003207A1

  公开（公告）日：2010-01-07

  UV-photoprotective, topically applicable cosmetic/dermatological compositions contain: (a) at least one dibenzoylmethane compound, (b) at least one 1,3,5-triazine compound that is photosensitive in the presence of a dibenzoylmethane compound, and (c) at least one siliceous s-triazine compound substituted with two aminobenzoate or aminobenzamide groups, or a tautomeric form thereof, the 1,3,5-triazine compounds being improvedly photostable in such compositions.

  紫外线光保护、可局部应用的化妆品/皮肤科学组合物包含：(a) 至少一种二苯甲酮类化合物，(b) 至少一种在存在二苯甲酮类化合物时对光敏感的1,3,5-三嗪类化合物，以及(c) 至少一种含有两个氨基苯甲酸酯或氨基苯酰胺基团或其互变异构体的含硅三嗪化合物，这些1,3,5-三嗪类化合物在这种组合物中具有改进的光稳定性。
• 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE
  申请人：Kubota Hideki

  公开号：US20080227785A1

  公开（公告）日：2008-09-18

  This invention relates to an anti-dementia agent which uses a BEC 1 potassium channel inhibitor as the active ingredient. It was proved that the BEC 1 potassium channel inhibitor has an action to improve learning disorder and is useful as a preventive or therapeutic agent for diseases, preferably dementia, in which the BEC 1 potassium channel is considered to be concerned. Illustratively, it was confirmed by an in vivo test that the BEC 1 potassium channel inhibitor has an action to improve learning disorder. Also, it was found that a compound having 2,4,6-triamino-1,3,5-triazine has a BEC 1 potassium channel inhibitory action.

  本发明涉及一种以BEC 1钾离子通道抑制剂作为活性成分的抗痴呆剂。已经证明，BEC 1钾离子通道抑制剂具有改善学习障碍的作用，并且作为预防或治疗剂是有用的，尤其是对于BEC 1钾离子通道与之相关的疾病，如痴呆症。例如，通过体内试验证实，BEC 1钾离子通道抑制剂具有改善学习障碍的作用。此外，还发现具有2,4,6-三氨基-1,3,5-三嗪的化合物具有BEC 1钾离子通道抑制作用。
• S-TRIAZINE DERIVATIVES CONTAINING AT LEAST TWO PARTICULAR SILANE AMINOBENZOATE OR SILANE AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COSMETIC COMPOSITIONS CONTAINING THESE DERIVATIVES; USES OF THE SAID S-TRIAZINE DERIVATIVES
  申请人：Richard Herve

  公开号：US20110097365A1

  公开（公告）日：2011-04-28

  The invention relates to novel s-triazine derivatives containing at least two particular silane aminobenzoate or silane aminobenzamide groups and to their cosmetic uses. The invention also relates to photoprotective compositions comprising s-triazine derivatives containing at least two particular grafted silane aminobenzoate or silane aminobenzamide groups as sunscreens that are active in the UV-B radiation range.

  本发明涉及一种新型的S-三嗪衍生物，其含有至少两个特定的硅烷氨基苯甲酸酯或硅烷氨基苯酰胺基团，以及它们在化妆品中的使用。本发明还涉及包含至少两个特定嫁接的硅烷氨基苯甲酸酯或硅烷氨基苯酰胺基团的S-三嗪衍生物作为活性成分的光保护组合物，用作紫外线B辐射范围内的防晒剂。
• DICHLORODIKETOPYRROLOPYRROLE PIGMENT, COLORING MATERIAL DISPERSION CONTAINING THE PIGMENT, AND PROCESS FOR PRODUCTION OF THE COLORING MATERIAL DISPERSION
  申请人：FUJIFILM Corporation

  公开号：EP2471876A1

  公开（公告）日：2012-07-04

  A coloring material dispersion, having: a particle growth inhibitor; and coloring material particulates of a dichlorodiketopyrrolopyrrole pigment, said coloring material particulates having an α type crystallinity degree from 0.65 to 0.90, a crystallite size from 6.0 to 13.0 nm in a direction of a (-151) crystal face, and a crystallite size of 5.0 to 23.0 nm in a direction of a (111) crystal face.

  一种着色材料分散液，其中包含：颗粒生长抑制剂；以及二氯二酮吡咯啉颜料的着色材料颗粒，所述着色材料颗粒的 α 型结晶度为 0.65 至 0.90，沿（-151）晶面方向的结晶粒径为 6.0 至 13.0 nm，沿（111）晶面方向的结晶粒径为 5.0 至 23.0 nm。
• US7375222B2
  申请人：——

  公开号：US7375222B2

  公开（公告）日：2008-05-20