1-chlorocarbonyl-2,6-dimethylpiperidine | 54486-12-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-chlorocarbonyl-2,6-dimethylpiperidine
• 英文别名: 2,6-Dimethylpiperidine-1-carbonyl chloride
• CAS: 54486-12-3
• 化学式: C₈H₁₄ClNO
• mdl: MFCD19281921
• 分子量: 175.658
• InChiKey: JOPVMXGJULJMLT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.875
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-chlorocarbonyl-2,6-dimethylpiperidine 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 4-Oxo-4H-chromene-2-carboxylic acid 2-[(2,6-dimethyl-piperidine-1-carbonyl)-ethyl-amino]-ethyl ester
  参考文献：
  名称：

  Synthesis and characterization of a cyclic acylammonium chloride

  摘要：

  DOI：

  10.1021/jo01291a039
• 作为产物：
  描述：

  2,6-二甲基哌啶 、 光气 以 苯 为溶剂， 反应 3.0h， 以to obtain 2,6-dimethylpiperidinoyl chloride的产率得到1-chlorocarbonyl-2,6-dimethylpiperidine
  参考文献：
  名称：

  Amidinoureas

  摘要：

  本发明涉及一种新型的苯基脲类化合物及其制备方法。这些化合物具有有效的降压作用，并对心血管系统产生活性。本发明还涉及一种治疗高血压症的方法。

  公开号：

  US04488993A1

文献信息

• Tetrazolinones as herbicides and intermediates
  申请人：NIHON BAYER AGROCHEM K.K.

  公开号：EP0820994A1

  公开（公告）日：1998-01-28

  The present invention relates to novel compounds and mixtures of geometrical isomers, which are represented by the formula: wherein R1 and R2independently of one another are C1-6 alkyl, C1-6 haloalkyl, C3-8 cycloalkyl, C2-6 alkenyl, C2-6 haloalkenyl, C3-6 alkynyl or optionally substituted phenyl; or R1 and R2, together with the nitrogen atom to which they are bonded, form a 5-membered or 6-membered heterocyclic ring which may be benzo-fused or which may be substituted by halogen or C1-4 alkyl; R3 is hydrogen or C1-6 alkyl; R4 is hydrogen or C1-6 alkyl; or R3 and R4, together with the carbon atoms to which they are bonded, form cyclopentylidene or cyclohexylidene; and R5 is C1-6 alkyl, C3-6 alkenyl or benzyl; further to processes and new intermediates for their production and to their use as herbicides.

  本发明涉及一类新的化合物及几何异构体的混合物，其由以下公式表示：其中R1和R2彼此独立地为C1-6烷基，C1-6卤代烷基，C3-8环烷基，C2-6烯基，C2-6卤代烯基，C3-6炔基或可选地被取代的苯基；或者R1和R2与它们所连接的氮原子一起形成一个可能被苯并环合的、5成员或6成员的杂环环，该环可能被卤素或C1-4烷基取代；R3是氢或C1-6烷基；R4是氢或C1-6烷基；或者R3和R4与它们所连接的碳原子一起形成环戊基亚基或环己基亚基；并且R5是C1-6烷基，C3-6烯基或苄基；进一步涉及到它们的制备过程和新中间体，以及它们作为除草剂的使用。
• PHOTOBASE GENERATOR
  申请人：Kuramoto Ayako

  公开号：US20110233048A1

  公开（公告）日：2011-09-29

  There is intended to provide the novel compounds which generate a base easily when irradiated with long wavelength light (active energy rays), a photobase generator containing the compounds and a photobase generation method, and the present invention relates to the compounds represented by the general formula [1], a photobase generator containing the compounds and a photobase generation method: (wherein, Ar represents any of groups with specific structures selected from the group consisting of an anthracenyl group, an anthraquinonyl group and a pyrenyl group; R 1 and R 2 each independently represent a hydrogen atom or a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, or represent ones which can form an alicyclic ring containing nitrogen atom(s) or an aromatic ring containing nitrogen atom(s) together with a nitrogen atom to which they are bound, which the rings having 3 to 8 carbon atoms which may have a substituent, R 3 and R 4 each independently represent a hydrogen atom, a linear, branched or acyclic alkyl group having 1 to 10 carbon atoms).

  本发明旨在提供当受长波长光（活性能量射线）照射时易于产生碱的新化合物，包含这些化合物的光碱发生器以及光碱生成方法，本发明涉及由通式[1]表示的化合物，包含这些化合物的光碱发生器以及光碱生成方法：（其中，Ar代表从蒽基团、蒽醌基团和芘基团中选择的具有特定结构的任何基团；R1和R2各自独立地代表氢原子或具有1至10个碳原子的直链、支链或环烷基基团，或表示能够与它们结合的氮原子形成含氮原子的脂环烷基环或含氮原子的芳香环，这些环具有3至8个碳原子，可能有取代基；R3和R4各自独立地代表氢原子，具有1至10个碳原子的直链、支链或非环烷基基团）。
• Treatment of hypertension with amidinoureas
  申请人：William H. Rorer, Inc.

  公开号：US04220658A1

  公开（公告）日：1980-09-02

  Novel phenylamidinourea compounds and processes for their preparation are described. These compounds have an effective degree of anti-hypertensive properties and exert activities on the cardiovascular system. A method for the treatment of hypertensive disorders is also described.

  本文介绍了新型苯基脲类化合物及其制备方法。这些化合物具有有效的降压作用，并对心血管系统产生作用。还介绍了一种治疗高血压疾病的方法。
• Treatment of diarrhea with amidinoureas
  申请人：William H. Rorer, Inc.

  公开号：US04115564A1

  公开（公告）日：1978-09-19

  A new class of chemical compounds and their process of preparation is described. These compounds have valuable properties as anti-diarrheal agents.

  描述了一种新的化合物类别及其制备过程。这些化合物具有抗腹泻药物的有价值特性。
• Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones
  申请人：NIHON BAYER AGROCHEM K.K.

  公开号：EP0646577A1

  公开（公告）日：1995-04-05

  1,4-Disubstituted-5(4H)-tetrazolinones of the formula (I) (wherein R¹, R² and R³ have the meanings given in the specification), which are known to be useful as herbicides, can be obtained in very good yields by reacting the corresponding 1-substituted-5(4H)-tetrazolinones with the corresponding carbamoyl chlorides in the presence of 4-dimethylaminopyridine.

  式 (I) 的 1,4-二取代-5(4H)-四唑啉酮 将相应的 1-取代-5(4H)-四唑啉酮与相应的氨基甲酰氯在 4-二甲氨基吡啶存在下进行反应，可获得收率极高的 1,4-二取代-5(4H)-四唑啉酮，该化合物已知可用作除草剂（其中 R¹、R² 和 R³ 的含义见说明书）。