2,5-diethyl-piperidine | 116836-21-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2,5-diethyl-piperidine
• 英文别名: 2,5-Diaethyl-piperidin；2,5-Diethylpiperidine
• CAS: 116836-21-6
• 化学式: C₉H₁₉N
• mdl: MFCD19218949
• 分子量: 141.257
• InChiKey: IZLHISLQJGXQCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 sodium 作用下， 生成 2,5-diethyl-piperidine
  参考文献：
  名称：

  Prausnitz, Chemische Berichte, 1892, vol. 25, p. 2394

  摘要：

  DOI：

文献信息

• Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same
  申请人：——

  公开号：US20040010011A1

  公开（公告）日：2004-01-15

  The invention relates to benzofuran or benzothiophene derivatives of general formula: 1 These compounds are of use as medicinal products, in particular in the treatment of pathological syndromes of the cardiovascular system.

  这项发明涉及一般式为苯并呋喃或苯并噻吩衍生物的化合物：1。这些化合物可用作药物产品，特别是用于治疗心血管系统病理综合征。
• Process for producing catalyst for alpha -olefin polymerization and process for producing alpha -olefin polymer
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20030134992A1

  公开（公告）日：2003-07-17

  There are provided a process for producing a catalyst for &agr;-olefin polymerization, which comprises the step of contacting (1) a solid catalyst component having Ti, Mg and a halogen as essential components, (2) an organoaluminum compound and (3) a compound having a —C—O—C—O—C— bond group in a closed ring structure with one another; and a process for producing an &agr;-olefin polymer, which comprises the step of homopolymerizing or copolymerizing an &agr;-olefin in the presence of a catalyst for &agr;-olefin polymerization produced by the above process.

  提供了一种生产烯烃聚合催化剂的工艺，该工艺包括以下步骤：(1)以 Ti、Mg 和卤素为主要成分的固体催化剂组分，(2)有机铝化合物和(3)在闭环结构中具有-C-O-C-O-C-键基的化合物相互接触；以及一种生产&agr;-烯烃聚合物的工艺，该工艺包括在上述工艺生产的&agr;-烯烃聚合催化剂存在下均聚或共聚&agr;-烯烃的步骤。
• Process for producing catalyst for alpha-olefin polymerization and process for producing alpha-olefin polymer
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20040092679A1

  公开（公告）日：2004-05-13

  There are provided a process for producing a catalyst for &agr;-olefin polymerization, which comprises the step of contacting (1) a solid catalyst component having Ti, Mg and a halogen as essential components, (2) an organoaluminum compound and (3) a compound having a —C—O—C—O—C— bond group in a closed ring structure with one another; and a process for producing an &agr;-olefin polymer, which comprises the step of homopolymerizing or copolymerizing an &agr;-olefin in the presence of a catalyst for &agr;-olefin polymerization produced by the above process.

  提供了一种生产烯烃聚合催化剂的工艺，该工艺包括以下步骤：(1)以 Ti、Mg 和卤素为主要成分的固体催化剂组分，(2)有机铝化合物和(3)在闭环结构中具有-C-O-C-O-C-键基的化合物相互接触；以及一种生产&agr;-烯烃聚合物的工艺，该工艺包括在上述工艺生产的&agr;-烯烃聚合催化剂存在下均聚或共聚&agr;-烯烃的步骤。
• AMINOALKOXYBENZOYL-BENZOFURANES OU BENZOTHIOPHENES, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS LES CONTENANT
  申请人：SANOFI-SYNTHELABO

  公开号：EP1315710A1

  公开（公告）日：2003-06-04
• UREA DERIVATIVES AND USES THEREOF
  申请人：Kala Pharmaceuticals, Inc.

  公开号：US20150072986A1

  公开（公告）日：2015-03-12

  The present invention provides novel compounds of any one of Formulae (I)-(III), and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I)-(III) and pharmaceutical compositions thereof that are mucus penetrating. The invention also provides methods and kits for using the inventive compounds, and pharmaceutical compositions thereof, for treating and/or preventing diseases associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor (e.g., vascular endothelial growth factor (VEGF)), such as proliferative diseases (e.g., cancers, benign neoplasms, inflammatory diseases, autoimmune diseases) and ocular diseases (e.g., macular degeneration, glaucoma, diabetic retinopathy, retinoblastoma, edema, uveitis, dry eye, blepharitis, and post-surgical inflammation) in a subject in need thereof.