(63)copper(II) nitrate

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 过渡金属氧阴离子化合物
• 英文名称: (63)copper(II) nitrate
• 英文别名: copper(II) nitrate；copper;nitrate
• 化学式: 2NO₃*Cu
• 分子量: 187.01
• InChiKey: GQPKMYBWFXDMIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.24
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  62.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (63)copper(II) nitrate 在 Cu-bipy-exchanged NaY-zeolite 作用下， 以 not given 为溶剂， 生成 mono(2,2'-bipyridine)copper(2+)
  参考文献：
  名称：

  An electron paramagnetic resonance study of mono(2,2′-bipyridine)copper(II) complexes formed in zeolite-Y

  摘要：

  DOI：

  10.1016/s0020-1693(00)94644-9
• 作为产物：
  描述：

  硝酸 、 Copper 以 硝酸 为溶剂， 生成 (63)copper(II) nitrate
  参考文献：
  名称：

  Novel tumor chemotherapeutic agents and tumor radio-imaging agents: Potential tumor pharmaceuticals of ternary copper(II) complexes

  摘要：

  Potential tumor chemotherapeutic agents and tumor radio-imaging agents of -Cu2+-salicylidene-amino acid Schiff bases-Phen (Bipy) ternary complexes have been designed and synthesized, their antitumor activity and tumor imaging of Cu-64 labeled ones have been tested in tumor-bearing mice. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2005.01.023

文献信息

• Thermodynamic stereoselectivity assisted by weak interactions in metal complexes. Chiral recognition of L/D-amino acids by the copper(II) complex of 6-deoxy-6-[4-(2-aminoethyl)imidazolyl]cyclomaltoheptaose
  作者：Raffaele P. Bonomo、Vincenzo Cucinotta、Giuseppe Maccarrone、Enrico Rizzarelli、Graziella Vecchio

  DOI：10.1039/b100443n

  日期：——

  Potentiometric and spectroscopic methods were used to investigate the stability and bonding details of the copper(II) complexes of β-cyclodextrin (β-CD) functionalized by histamine through the imidazole N-1 (CDmh) and a number of enantiomeric pairs of amino acidates (AaO−) where AaO− is alaninate (AlaO−), phenylalaninate (PheO−) or tryptophanate (TrpO−). Stability constant values were determined at 25 °C and I = 0.1 mol dm−3 (KNO3). Enantioselectivity was observed in the copper(II) mixed complex formation of L/D-TrpO− in aqueous solution and [Cu(CDmh)(L-TrpO)]+ was seen as being favoured over [Cu(CDmh)(D-TrpO)]+. In contrast, the AlaO− systems did not show any differences in the stability of copper(II) diastereomeric ternary complexes. The c.d. spectra of the complexes containing aromatic L-amino acids showed much higher intensity (Δε) compared with the spectra for the corresponding D-amino acids, the difference Δ(Δε) increasing in proportion to the size of the side chain. Subtle differences were found to exist between the ESR parameters of the diastereomeric complexes with TrpO−. However, these tended to disappear upon the addition of a less polar solvent. The results obtained are consistent with a model where the complexation of the L enantiomer to copper already bound to the histamine residue is favoured by the inclusion of the aromatic side chain in the cyclodextrin cavity, this in turn being due to the preferential cis arrangement of the amino nitrogens in the two ligands.

  采用电位法和光谱法研究了通过咪唑N-1（CDmh）和若干对映异构体氨基酸盐（AaO−）功能化的β-环糊精（β-CD）的铜（II）络合物的稳定性和结合细节，其中AaO−为丙氨酸盐（AlaO−）、苯丙氨酸盐（PheO−）或色氨酸盐（TrpO−）。在25 °C和I = 0.1 mol dm−3（KNO3）条件下测定了稳定常数值。在水溶液中，L/D-TrpO−的铜（II）混合络合物形成过程中观察到优先选择性，并且[Cu(CDmh)(L-TrpO)]+被视为优于[Cu(CDmh)(D-TrpO)]+。相比之下，AlaO−系统在铜（II）非对称三元络合物的稳定性上没有表现出任何差异。含有芳香族L-氨基酸的络合物的圆二色谱（c.d.）光谱的强度（Δε）明显高于相应D-氨基酸的光谱，差异Δ(Δε)随侧链大小的增加而增大。发现TrpO−的非对映体络合物的电子自旋共振（ESR）参数之间存在细微差别。然而，当加入极性较小的溶剂时，这些差别倾向于消失。获得的结果与以下模型一致：L对映体与已经与组胺残基结合的铜的络合在环糊精腔内芳香侧链的包容性促进下更为有利，这反过来是由于两个配体中氨基氮的优先顺式排列。
• Room-temperature synthesis of mesoporous CuO and its catalytic activity for cyclohexene oxidation
  作者：Xinxin Sang、Jianling Zhang、Tianbin Wu、Bingxing Zhang、Xue Ma、Li Peng、Buxing Han、Xinchen Kang、Chengcheng Liu、Guanying Yang

  DOI：10.1039/c5ra12808k

  日期：——

  CuO nanoleaves with a mesoporous structure have been synthesized in the presence of triethylamine at room temperature. The mesoporous CuO nanoleaves exhibit excellent catalytic activity for solvent-free cyclohexene oxidation with oxygen.

  在三乙胺存在下，室温下合成了具有介孔结构的CuO纳米叶片。这些介孔CuO纳米叶片对无溶剂环己烯氧化反应具有优异的催化活性。
• UV-Vis and EPR spectroscopic study of copper(II) complexes with bis(benzimidazol-2-yl) ligands
  作者：Raffaele P. Bonomo、Enrico Rizzarelli、Mario Bressan、Antonio Morvillo

  DOI：10.1016/s0020-1693(00)87925-6

  日期：1991.8

  Abstract Copper(II) complexes with bis(benzimidazol-2-yl) ligands of the type Bz(CH 2 ) n -X-(CH 2 ) n Bz (where Bz=benzimidazol-2-yl; XO, S or CH 2 ; n =1, 2) have been characterized in solution by UV-Vis and EPR spectroscopy. Mono complexes with O or S donor atom containing ligands have square-pyramidal stereochemistries, while bis complexes have pseudo-octahedral geometries with four nitrogen donors

  摘要具有Bz（CH 2）n -X-（CH 2）n Bz类型的双（苯并咪唑-2-基）配体的铜（II）配合物（其中Bz =苯并咪唑-2-基; X = O，S或CH 2； n = 1，2）已通过紫外可见光谱和EPR光谱法在溶液中表征。具有包含O或S供体原子的配体的单分子络合物具有方形锥体的立体化学，而双络合物具有伪八面体的几何构型，在赤道平面上具有四个氮供体，两个杂原子占据顶位。具有X ＝ CH 2和n ＝ 2的配体的单和双配合物已经扭曲了八面体的几何形状，其中两个溶剂分子参与了顶端位置。具有X ＝ CH 2和n ＝ 1的配体的配合物的实验结果表明该配体表现为单齿。
• Unusual Noncovalent Interaction Between the Chelated Cu(II) Ion and the π Bond in the Vitamin B₁₃ Complex, <i>cis</i>-Diammine(orotato)copper(II): Theoretical and Vibrational Spectroscopy Studies
  作者：K. Helios、R. Wysokiński、W. Zierkiewicz、L. M. Proniewicz、D. Michalska

  DOI：10.1021/jp901912v

  日期：2009.6.11

  chelated Cu(II) complex and ethylene amounts to −7.33 kcal mol−1, which is similar to that determined for stacked uracil dimer. It is concluded that the London dispersion energy plays a significant role in the noncovalent interaction between the chelated Cu(II) ion and the uracilate ring in the crystal of cis-[Cu(oro)(NH3)2]. Many copper enzymes in their active sites contain the chelated Cu(II) ion and

  具有维生素B 13（乳清酸），顺式[[Cu（oro）（NH 3）2 ]的Cu（II）配合物的晶体结构表明，螯合的Cu（II）之间存在异常的，非共价的π型相互作用离子和尿嘧啶环的C═C键[Michalska et al。多面体2007，26，4303]。在这项工作中，这种相互作用的起源和强度得到了彻底的研究。使用不受限制的密度泛函理论方法，B3LYP和新开发的M05-2X泛函，对标题复合物的分子结构和振动光谱进行了全面的研究。为了比较，还进行了UMP2级别的计算。DFT计算中已经采用了多种基础集，包括aug-cc-pVTZ，D95V（d，p），SDD和LanL2DZ。的63铜/ 65铜同位素替代技术用于识别红外光谱中的铜配体振动。在计算出的势能分布PED的基础上，对标题配合物的FT-IR和拉曼光谱中的所有波段进行了明确分配。结果表明，顺式-[Cu（oro）（NH 3）2 ]的拉曼光谱中1210
• Nitrogen oxide interaction with copper complexes formed by small peptides belonging to the prion protein octa-repeat region
  作者：Raffaele P. Bonomo、Giuseppe Pappalardo、Enrico Rizzarelli、Anna M. Santoro、Giovanni Tabb?、Laura I. Vagliasindi

  DOI：10.1039/b617408f

  日期：——

  The interaction between NO and copper(II) complexes formed by peptides coming from the N-terminal prion protein octa-repeat region was studied. Aqueous solutions of the Cu-Ac-HGGG-NH2 and the Cu-Ac-PHGGGWGQ-NH2 systems around pH 7.5 were tested after the addition of NONOates as a source of NO. UV-Vis, room temperature and frozen solution EPR spectra showed the occurrence of copper(II) reduction in all these complexes. The reduction of these complexes is probably mediated by the formation of a labile NO adduct, which, after re-oxidation, leads to a relatively stable NO2− adduct through the apical coordination along the void site of their square pyramidal structure. In fact, the most significant shifts in EPR magnetic parameters (g‖ and A‖ or giso and Aiso) as well as in the optical parameters (λmax and εmax) gave a reason for geometrical changes of the copper coordination polyhedron from a distorted square pyramid to a pseudo-octahedron. The presence of oxygen in the aqueous solution hindered the reduction ability of NO towards copper, but it made it easier to return to the original species. In order to elucidate the possible mechanism of this interaction, the reduction of copper complexed by these ligands was followed by means of zinc powder addition. The further addition of nitrite to the solution containing reduced copper led to the conclusion that nitrite could easily form an adduct, which after re-oxidation presented the same spectral features of the species obtained when the NO interaction was followed. The complexity of this interaction could involve both an inner or an outer-sphere electron transfer mechanism.

  研究了由来自N端朊病毒蛋白八重重复区肽形成的NO和铜（II）络合物之间的相互作用。在加入作为NO来源的NONO酸盐后，测试了pH值约为7.5的Cu-Ac-HGGG-NH2和Cu-Ac-PHGGGWGQ-NH2系统的水溶液。紫外-可见光、室温和冷冻溶液EPR光谱显示在所有这些络合物中发生了铜（II）还原。这些络合物的还原可能通过形成不稳定的NO加合物来介导，该加合物在重新氧化后，通过沿其方形金字塔结构的空位处的顶点配位，形成相对稳定的NO2-加合物。事实上，EPR磁参数（g‖和A‖或giso和Aiso）以及光学参数（λmax和εmax）的最大变化，为铜配位多面体从扭曲的方形金字塔到伪八面体的几何变化提供了理由。水溶液中氧的存在阻碍了NO对铜的还原能力，但它使还原更容易恢复到原始物种。为了阐明这种相互作用的可能机制，通过添加锌粉来跟踪这些配体络合铜的还原。进一步向含有还原铜的溶液中添加亚硝酸盐，得出的结论是亚硝酸盐很容易形成加合物，该加合物在重新氧化后呈现出与跟踪NO相互作用时获得的物种相同的光谱特征。这种相互作用的复杂性可能涉及