N-Acetyl-2-vinyl-sulfonyl-aethylamin | 20854-27-7

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: N-Acetyl-2-vinyl-sulfonyl-aethylamin
• 英文别名: N-(2-ethenylsulfonylethyl)acetamide
• CAS: 20854-27-7
• 化学式: C₆H₁₁NO₃S
• 分子量: 177.224
• InChiKey: MZRQTACSWPSFPJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  71.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-Acetyl-2-vinyl-sulfonyl-aethylamin 在 盐酸 作用下， 生成 乙胺,2-(乙烯基磺酰)-
  参考文献：
  名称：

  Schoeberl,A.; Biedermann,M., Justus Liebigs Annalen der Chemie, 1968, vol. 716, p. 37 - 46

  摘要：

  DOI：
• 作为产物：
  描述：

  N-Acetyl-2-vinyl-mercapto-aethylamin 在 过氧乙酸 作用下， 生成 N-Acetyl-2-vinyl-sulfonyl-aethylamin
  参考文献：
  名称：

  Schoeberl,A.; Biedermann,M., Justus Liebigs Annalen der Chemie, 1968, vol. 716, p. 37 - 46

  摘要：

  DOI：

文献信息

• Multi-armed, monofunctional, and hydrolytically stable derivatives of poly (ethylene glycol) and related polymers for modification of surfaces and molecules
  申请人：Harris J. Milton

  公开号：US20090054590A1

  公开（公告）日：2009-02-26

  Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms poly a and poly b , respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEG a and mPEG b have the structure CH 3 O—(CH 2 CH 2 O) n CH 2 CH 2 — wherein n may be the same or different for poly a - and poly b - and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.
• MULTI-ARMED, MONOFUNCTIONAL, AND HYDROLYTICALLY STABLE DERIVATIVES OF POLY(ETHYLENE GLYCOL) AND RELATED POLYMERS FOR MODIFICATION OF SURFACES AND MOLECULES
  申请人：Harris J. Milton

  公开号：US20100298496A1

  公开（公告）日：2010-11-25

  Multi-armed, monofunctional, and hydrolytically stable polymers are described having the structure wherein Z is a moiety that can be activated for attachment to biologically active molecules such as proteins and wherein P and Q represent linkage fragments that join polymer arms poly a and poly b , respectively, to central carbon atom, C, by hydrolytically stable linkages in the absence of aromatic rings in the linkage fragments. R typically is hydrogen or methyl, but can be a linkage fragment that includes another polymer arm. A specific example is an mPEG disubstituted lysine having the structure where mPEG a and mPEG b have the structure CH 3 O—(CH 2 CH 2 O) n CH 2 CH 2 — wherein n may be the same or different for poly a - and poly b - and can be from 1 to about 1,150 to provide molecular weights of from about 100 to 100,000.
• US7419600B2
  申请人：——

  公开号：US7419600B2

  公开（公告）日：2008-09-02
• US7786221B2
  申请人：——

  公开号：US7786221B2

  公开（公告）日：2010-08-31
• US8354477B2
  申请人：——

  公开号：US8354477B2

  公开（公告）日：2013-01-15