[4-(5-Bromopentoxy)phenyl]-(4-octylphenyl)diazene | 215096-01-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: [4-(5-Bromopentoxy)phenyl]-(4-octylphenyl)diazene
• CAS: 215096-01-8
• 化学式: C₂₅H₃₅BrN₂O
• 分子量: 459.47
• InChiKey: HTZAVQCGTVRVPW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.5
• 重原子数：
  29
• 可旋转键数：
  15
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  34
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  [4-(5-Bromopentoxy)phenyl]-(4-octylphenyl)diazene 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 5-[4-[(4-Octylphenyl)diazenyl]phenoxy]pentane-1-thiol
  参考文献：
  名称：

  A Convenient Synthesis of Novel Mercapto-Ended Azobenzene Derivatives

  摘要：

  Treatment of the product from the Diazo-Coupling reaction of p-alkylaniline with 1,3-dibromopropane in THF affords intermediate compounds n-C(n)H(2n+1)AzoO(CH2)(m)Br. Subsequent treatment of these intermediate with thiourea in ethanol at reflux temperature leads to the desired azobenzene derivatives, n-C(n)H(2n+1)AzoO(CH2)(m)SH (n=4,6,8,10,12; m=3,5), in good yield. The structure data of these new compounds was presented in detail.

  DOI：

  10.1080/00397919808004930
• 作为产物：
  描述：

  4-辛基苯胺 在 盐酸 、 氢氧化钾 、 sodium carbonate 、 sodium nitrite 作用下， 以 四氢呋喃 、 水 为溶剂， 生成 [4-(5-Bromopentoxy)phenyl]-(4-octylphenyl)diazene
  参考文献：
  名称：

  A Convenient Synthesis of Novel Mercapto-Ended Azobenzene Derivatives

  摘要：

  Treatment of the product from the Diazo-Coupling reaction of p-alkylaniline with 1,3-dibromopropane in THF affords intermediate compounds n-C(n)H(2n+1)AzoO(CH2)(m)Br. Subsequent treatment of these intermediate with thiourea in ethanol at reflux temperature leads to the desired azobenzene derivatives, n-C(n)H(2n+1)AzoO(CH2)(m)SH (n=4,6,8,10,12; m=3,5), in good yield. The structure data of these new compounds was presented in detail.

  DOI：

  10.1080/00397919808004930

文献信息

• A Convenient Synthesis of Novel Mercapto-Ended Azobenzene Derivatives
  作者：Li Haiying、Liu Zhongfan

  DOI：10.1080/00397919808004930

  日期：1998.10

  Treatment of the product from the Diazo-Coupling reaction of p-alkylaniline with 1,3-dibromopropane in THF affords intermediate compounds n-C(n)H(2n+1)AzoO(CH2)(m)Br. Subsequent treatment of these intermediate with thiourea in ethanol at reflux temperature leads to the desired azobenzene derivatives, n-C(n)H(2n+1)AzoO(CH2)(m)SH (n=4,6,8,10,12; m=3,5), in good yield. The structure data of these new compounds was presented in detail.