Bis(piperidino)trisulfide | 25029-88-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: Bis(piperidino)trisulfide
• 英文别名: 1,1'-trisulfanediyl-bis-piperidine；dipiperidino-trisulfane；Dipiperidino-trisulfan；Dipiperidino-trisulfid；Piperidintrisulfid；1,1'-(Trisulfane-1,3-diyl)dipiperidine；1-(piperidin-1-yltrisulfanyl)piperidine
• CAS: 25029-88-3
• 化学式: C₁₀H₂₀N₂S₃
• 分子量: 264.48
• InChiKey: TXDSFYCFEQVCOB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  82.4
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  哌啶 在 lead(II) oxide 、 sulfur 、 苯 作用下， 生成 Bis(piperidino)trisulfide
  参考文献：
  名称：

  Levi, Gazzetta Chimica Italiana, 1931, vol. 61, p. 295

  摘要：

  DOI：

文献信息

• Reactions of 5-(arylimino)-4-chloro-5H-1,2,3-dithiazoles with primary and secondary alkylamines: novel synthesis of (arylimino)cyanomethyl alkylamino disulfides and their mechanisms of formation
  作者：Hyunil Lee、Kyongtae Kim

  DOI：10.1021/jo00077a017

  日期：1993.12

  Reactions of 5-(arylimino)-4-chloro-5H-1,2,3-dithiazoles with alkylamines such as isopropylamine, piperidine, pyrrolidine, and diethylamine in methylene chloride at room temperature gave (arylimino)cyanomethyl alkylamino disulfides (14-83%) along with N'-aryl-N-alkylcyanoformamidines (O-88%). The yields of the latter increase and those of the former decrease with the concentration of the amine. In addition, some of the latter compounds were independently synthesized by treatment of the former with cyclic amines such as piperidine, pyrrolidine, and morpholine in methylene chloride at room temperature (22-97%). The results indicate that the former compounds are involved as intermediates in the formation of the latter in these reactions. However, when [(p-nitrophenyl)-imino] cyanomethyl (pentane-1,5-diyl)amino disulfide was treated with sterically bulky amines such as tert-butyl- and diethylamines at reflux and room temperature, respectively, cyanoformamidines having a piperidine moiety rather than tert-butyl- and diethylamino groups were obtained as the only isolable products. Two pathways which involve initially either direct nucleophilic attack of alkylamines on the imino carbon or on the sulfur a to the amino group of (arylimino)cyanomethyl alkylamino disulfides are proposed to rationalize the results.
• US4168981A
  申请人：——

  公开号：US4168981A

  公开（公告）日：1979-09-25
• Levi, Gazzetta Chimica Italiana, 1931, vol. 61, p. 295
  作者：Levi

  DOI：——

  日期：——