氯-(3-乙氧基丙基)-二甲基硅烷 | 142801-33-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 氯-(3-乙氧基丙基)-二甲基硅烷
• 中文别名: (3-乙氧基丙基)二甲基氯硅烷
• 英文名称: (3-ethoxypropyl)dimethylchlorosilane
• 英文别名: Chloro(3-ethoxypropyl)dimethylsilane；chloro-(3-ethoxypropyl)-dimethylsilane
• CAS: 142801-33-0
• 化学式: C₇H₁₇ClOSi
• 分子量: 180.75
• InChiKey: YTONRUGDXHJSHB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.86
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  氯-(3-乙氧基丙基)-二甲基硅烷 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 以71%的产率得到(3-ethoxypropyl)dimethylsilane
  参考文献：
  名称：

  Kira, Mitsuo; Hino, Takakazu; Sakurai, Hideki, Journal of the American Chemical Society, 1992, vol. 114, # 17, p. 6697 - 6700

  摘要：

  DOI：
• 作为产物：
  描述：

  乙基烯丙基醚 、 二甲基一氯硅烷 在 dihydrogen hexachloroplatinate 作用下， 反应 12.0h， 以50%的产率得到氯-(3-乙氧基丙基)-二甲基硅烷
  参考文献：
  名称：

  Kira, Mitsuo; Hino, Takakazu; Sakurai, Hideki, Journal of the American Chemical Society, 1992, vol. 114, # 17, p. 6697 - 6700

  摘要：

  DOI：

文献信息

• Mechanistic insights into the hydrosilylation of allyl compounds – Evidence for different coexisting reaction pathways
  作者：Peter Gigler、Markus Drees、Korbinian Riener、Bettina Bechlars、Wolfgang A. Herrmann、Fritz E. Kühn

  DOI：10.1016/j.jcat.2012.06.006

  日期：2012.11

  The hydrosilylation of allyl compounds is often accompanied by the formation of high amounts of byproducts. The formation processes have not been fully understood so far. In this work, the allyl hydrosilylation mechanism is investigated in detail and experimental and theoretical evidence for multiple, coexisting reaction pathways is provided. Based on earlier reports and the observations during an extensive catalytic study, different pathways, leading to the observed byproducts, were identified and proven by labeling experiments and DFT calculations. Oxidative addition of the silane and the insertion of the allyl compound into the Pt-H bond turned out to be the crucial, selectivity-determining steps within the catalytic cycle. Based on these findings, it should be possible to systematically influence these steps and pave the way to a rational and straightforward design of more selective catalysts. (C) 2012 Published by Elsevier Inc.
• Mechanistic insights into the iridium-catalyzed hydrosilylation of allyl compounds
  作者：Korbinian Riener、Teresa K. Meister、Peter Gigler、Wolfgang A. Herrmann、Fritz E. Kühn

  DOI：10.1016/j.jcat.2015.09.003

  日期：2015.11

  The hydrosilylation of allyl compounds is very important for the industrial production of gamma-substituted propylsilanes; however, it is also a process known to suffer from either substantial selectivity issues or short catalyst lifetimes. While there are reports on the platinum-catalyzed variant, this study is the first comprehensive work on the more recently employed iridium-catalyzed process. A combination of stoichiometric and catalytic experiments as well as reactions with isotope-labeled compounds is used to elucidate the critical parameters influencing the catalytic performance and to identify the main deactivation pathways. This report is intended to pave the way toward the optimization of current iridium-catalyzed processes and the design and synthesis of improved catalyst structures. (C) 2015 Elsevier Inc. All rights reserved.
• Kira, Mitsuo; Hino, Takakazu; Sakurai, Hideki, Journal of the American Chemical Society, 1992, vol. 114, # 17, p. 6697 - 6700
  作者：Kira, Mitsuo、Hino, Takakazu、Sakurai, Hideki

  DOI：——

  日期：——