sodium 2-propaneselenolate | 37773-08-3

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: sodium 2-propaneselenolate
• 英文别名: sodium isopropylselenol；propane-2-selenol; sodium salt；sodium;propane-2-selenolate
• CAS: 37773-08-3
• 化学式: C₃H₇Se*Na
• 分子量: 145.038
• InChiKey: QXEKVIINXWGHAL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -2.01
• 重原子数：
  5.0
• 可旋转键数：
  0.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  sodium 2-propaneselenolate 、 5-氯-2-戊酮 以40%的产率得到
  参考文献：
  名称：

  PARR, W. J. E., J. CHEM. SOC. PERKIN TRANS., 1981, N 12, 3002-3007

  摘要：

  DOI：
• 作为产物：
  描述：

  二异丙基二硒醚 在 sodium tetrahydroborate 作用下， 以 甲醇 、 苯 为溶剂， 生成 sodium 2-propaneselenolate
  参考文献：
  名称：

  Synthesis and evaluation of 24-(isopropyl[75Se]seleno)chol-5-en-3.beta.-ol

  摘要：

  Selenium-75-labeled 24-(isopropylseleno)chol-5-en-3 beta-ol (4) has been prepared by reaction of sodium isopropyl-[75Se]selenol [( 75Se]2) with 3 beta-acetoxy-24-bromochol-5-ene (3). This new 75Se-labeled adrenal imaging agent shows pronounced adrenal uptake in rats. The concentration of radioactivity in rat adrenals increased steadily from 1 to 24 h after injection and then decreased slowly over the 21-day period. After 3 days the adrenal/blood and adrenal/liver ratios were 85:1 and 32:1, respectively, which are sufficient for adrenal imaging by single photon techniques. After 6 h the adrenal/blood ratio was 17:1 and the adrenal/liver ratio was 7:1. We propose that these ratios are sufficiently high for positron emission tomography of the adrenals. The absorbed radiation dose values to human organs have been estimated for the 75Se- and 73Se-labeled agent.

  DOI：

  10.1021/jm00364a035

文献信息

• Synthesis, structure and properties of di- and tetranuclear manganese(II) chalcogenolate complexes [Mn2(SC3H7)6]2−, [Mn2(SCH3)6]2−, [Mn2(SeC3H7)6]2−, [Mn4(SC3H7)6Cl4]2− and [Mn4(SeC3H7)6Br4]2−
  作者：Hans-Oscar Stephan、Gerald Henkel

  DOI：10.1016/0277-5387(95)00232-h

  日期：1996.2

  Abstract Reaction of 1 : 3 molar ratio mixtures of MnCl2 and NaSR in MeCN/DMF gave [Mn2(SR)6]2− (5a: R = Pri; 5b : R = Me), which were isolated as [Me4N]2[Mn2(SR)6] (1a: R = Pri; 1b: R = Me). In a similar way, [Me4N]2[Mn2(SePri)6] (2) could be obtained. Compounds, 1a and 2 are isotypic. The metal-sulphur (selenium) cores of 5a, 5b and [Mn2(SePri)6]2− (6) consist of two MnX4 tetrahedra connected via

  摘要MnCl2和NaSR摩尔比为1：3的混合物在MeCN / DMF中的反应生成[Mn2（SR）6] 2-（5a：R = Pri; 5b：R = Me），分离为[Me4N] 2 [ Mn 2（SR）6]（1a：R ＝ Pri； 1b：R ＝ Me）。以类似的方式，可以获得[Me 4 N] 2 [Mn 2（SePri）6]（2）。化合物1a和2是同型的。5a，5b和[Mn2（SePri）6] 2-（6）的金属硫（硒）芯由两个通过共同边连接的MnX4四面体组成。讨论了与相关复合物的结构相似性。1a和2分别与2当量的MnCl2和MnBr2在乙腈中反应，分别得到[Me4N] 2 [Mn4（SPri）6Cl4]（3）和[Me4N] 2 [Mn4（SePri）6Br4]（bd4。复合阴离子[Mn4（SPri）6Cl4] 2-（7）和[Mn4（SePri）6Br4] 2-（8）是具有金刚烷型Mn4X6骨
• Di-μ-aqua-bis[(trimethanol-<i>O</i>)sodium]<i>anti</i>-bis(μ-2-propanethiolato-<i>S</i>:<i>S</i>)bis[bis(2-propanethiolato-<i>S</i>)iron(II)] and bis(benzyltrimethylammonium)<i>anti</i>-bis(μ-2-propaneselenolato-<i>Se</i>:<i>Se</i>)bis[bis(2-propaneselenolato-<i>Se</i>)iron(II)]
  作者：R. Hauptmann、J. Lackmann、C. Chen、G. Henkel

  DOI：10.1107/s0108270199003704

  日期：1999.7.15

  In the [Fe-2((SC3H7)-C-i)(6)](2-) and [Fe-2((SeC3H7)-C-i)(6)](2-) complex anions of the title compounds, [Na-2(CH4O)(6)(H2O)(2)][Fe-2(C3H7S)(6)] and (C10H16N)(2)[Fe-2(C3H7Se)(6)], the Fe atoms are coordinated by four chalcogen atoms in a distorted tetrahedral fashion. The FeE4 tetrahedra of the Fe2E6 frameworks (E = S or Se) share a common edge. The central Fe2E2 unit is an exactly planar rhomb with acute M-E-M angles. The oxidation state of iron is +2. The [Fe-2(S2C3H7)(6)](2-) anion was crystallized with the novel counter-cation [(MeOH)(3)Na(H2O)(2)Na(MeOH)(3)](2+).
• Stephan, Hans-Oskar; Henkel, Gerald, Angewandte Chemie, 1994, vol. 106, p. 2422 - 2424
  作者：Stephan, Hans-Oskar、Henkel, Gerald

  DOI：——

  日期：——
• Mueller, Arnd; Henkel, Gerald, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1997, vol. 52, # 12, p. 1501 - 1509
  作者：Mueller, Arnd、Henkel, Gerald

  DOI：——

  日期：——