3-Phenylsalicylsaeurephenylester | 3072-89-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: 3-Phenylsalicylsaeurephenylester
• 英文别名: 2-hydroxy-biphenyl-3-carboxylic acid phenyl ester；2-Hydroxy-biphenyl-3-carbonsaeure-phenylester；Phenyl m-phenyl-salicylate；phenyl 2-hydroxy-3-phenylbenzoate
• CAS: 3072-89-7
• 化学式: C₁₉H₁₄O₃
• 分子量: 290.318
• InChiKey: SKWHAOGOTDCDFQ-UHFFFAOYSA-N

物化性质

• 熔点：
  90-92 °C
• 沸点：
  436.5±33.0 °C(Predicted)
• 密度：
  1.227±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-Phenylsalicylsaeurephenylester 生成 2-methoxy-biphenyl-3-carboxylic acid dimethylamide
  参考文献：
  名称：

  Specific immune response to parietaria judaica plant profilin: a low t cell proliferative response supports high ige and skin prick test

  摘要：

  Background: allergic disease caused by Parietaria judaica (Pj) has been widely documented in Mediterranean area. Profilins have been identified as widely distributed allergenic proteins. The role of Pj profilin in specific immune response in Pj-sensitized patients is unknown. Methods: skin prick test and determination of specific and total IgE levels in serum were performed in all patients (n = 28) and non-allergic controls (n = 18). Peripheral blood mononuclear cells (PBMC) were isolated from both groups and stimulated with crude extract or highly purified Pj profilin. The production of type I and type II cytokines was determined by specific and polyclonal stimuli in patients and controls. T-cell lines specific to Pj profilin were established and cross-reactivity with another highly purified profilin from Phleum pratense (Phl p) was evaluated. Results: Pj profilin-sensitized patients showed a small but significantly increased in T-cell proliferative response to this profilin compared with non-atopic controls. The production of interleukin (IL)-4 and interferon (IFN)-γ in response to the specific stimulus was undetectable. However, the production of IL-4 in response to a polyclonal stimulus [phytohemagglutinin (PHA)] was significantly higher in atopic patients than in controls. The T-cell response did not correlate with the magnitude of response to skin prick tests with Pj profilin or with Pj-specific serum IgE levels. In addition, the production of IL-4 in response to a polyclonal stimulus (PHA) did not correlate with the individual skin prick tests to Pj profilin or with Pj-specific IgE levels in serum. The T-cell lines tested showed no cross-reactivity with Phl p profilin. Conclusions: our results suggest that Pj profilin is partly responsible for the T-cell-mediated response in patients allergic to Pj. The high skin reactivity to Pj profilin is these patients was accompanied by a small increase in the T-cell response to this profilin. The response was highly specific since Pj profilin specific T-cell lines showed no cross-reactivity with a highly homologous profilin from Phl p. The lack of correlation between the proliferative T-cell response and polyclonal IL-4 production with allergen-specific serum IgE and skin reactivity probably indicates that some of the responding T-cells may be involved in immune reactions other than those supporting IgE production.

  DOI：

  10.1016/s0301-0546(02)79092-7
• 作为产物：
  描述：

  3-苯基水杨酸 在 氯化亚砜 作用下， 生成 3-Phenylsalicylsaeurephenylester
  参考文献：
  名称：

  Woroshzow; Troschtschenko, Zhurnal Obshchei Khimii, 1938, vol. 8, p. 431,433

  摘要：

  DOI：

文献信息

• Emulsion adhesive composition and process for production thereof
  申请人：Chisso Corporation

  公开号：EP0406828A1

  公开（公告）日：1991-01-09

  An emulsion adhesive composition comprises: (i) an adhesive synthetic resin and (ii) a polyolefin and/or a hydrogenated block copolymer composed of an aromatic vinyl compound and an aliphatic diene polymer blocks, and each of the polyolefin and the hydrogenated block copolymer contains at least one functional group selected from carboxylic anhydride, carboxyl, glycidyl, hydroxyl, amido and alkoxysilyl groups. A photostabilizer may be incorporated into the composition in which said component (ii) may contain chloro. The emulsion adhesive composition can be used for adhering a highly crystalline resin molded article to an optional material without a complicated surface treatment, and can have a light resistance and storing stability.

  一种乳液粘合剂组合物包括：(i) 一种粘合剂合成树脂和 (ii) 一种聚烯烃和/或一种由芳香族乙烯基化合物和脂肪族二烯聚合物嵌段组成的氢化嵌段共聚物，聚烯烃和氢化嵌段共聚物各自含有至少一个选自羧酸酐、羧基、缩水甘油基、羟基、氨基和烷氧基硅烷基的官能团。组合物中可加入光稳定剂，其中所述成分 (ii) 可含有氯。 该乳液粘合剂组合物可用于将高结晶性树脂模塑品粘合到可选材料上，无需复杂的表面处理，并具有耐光性和储存稳定性。
• Nakajima et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1956, vol. 76, p. 1211
  作者：Nakajima et al.

  DOI：——

  日期：——
• Buu-Hoi et al., Bulletin de la Societe Chimique de France, 1956, p. 363,365
  作者：Buu-Hoi et al.

  DOI：——

  日期：——
• N-(4-hydroxyphenyl)-3-phenylsalicylamide
  申请人：CUTTER LAB

  公开号：US02773096A1

  公开（公告）日：1956-12-04
• US5319016A
  申请人：——

  公开号：US5319016A

  公开（公告）日：1994-06-07