lithium amide

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 碱金属有机物
• 英文名称: lithium amide
• 英文别名: lithium;azanide
• 化学式: H₂N*Li
• 分子量: 22.9636
• InChiKey: AFRJJFRNGGLMDW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.28
• 重原子数：
  2
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

ADMET

毒理性

• 毒性总结

识别和使用：锂酰胺是一种白色结晶性粉末，略微溶于乙醇、液氨，不溶于无水醚、苯、二甲苯和甲苯。它用于克莱森缩合；腈和酮的烷基化；乙炔化合物的合成，以及炔烃醇的合成。它用于有机合成，包括抗组胺药和其他药物。人类暴露和毒性：锂酰胺对皮肤、眼睛和粘膜有强烈的刺激性。动物研究：动物口服或静脉注射锂后急性锂中毒的最显著症状是厌食、恶心、呕吐、腹泻和流涎，伴有体重减轻、脱水和体温下降。对中枢神经系统的影响表现为肌肉无力、极度烦躁、昏迷和抽搐；对心脏的影响表现为心电图的改变，包括房室传导阻滞或心室颤动；对肾脏的影响表现为少尿、血蛋白氮升高和肾小管上皮细胞的变性变化。通过口服锂给14只新生大鼠，诱导了慢性肾功能衰竭。7只大鼠治疗了8周，随后无锂治疗8周（Li/C组），7只大鼠治疗了16周（Li/Li组）。测量了血浆尿素和肾脏浓缩能力，并通过血管灌注固定了一个肾脏。估计了平均肾小球体积以及单个肾小球的体积。此外，在连续切片上调查了肾小球与近端小管的结构完整性。没有硬化的肾小球。在Li/C组和Li/Li组中，分别只有37.6%和27.9%的肾小球连接到正常的近端小管，其余大部分肾小球是无小管的。Li/C组中肾小球体积没有变化，Li/Li组中肾小球体积减少了40%。锂处理组的肾小球体积个体内变异是对照组的约10倍。连接到正常近端小管的肾小球体积最大，Li/C组中比Li/Li组更频繁地遇到肥大的肾小球。血浆尿素与未连接到正常近端小管的肾小球比例之间存在显著正相关。虽然有迹象表明锂治疗后对胎儿有不利影响，但在大鼠、兔或灵长类动物中并未观察到。这个剂量对大鼠足以产生母体毒性和对哺乳期母鼠后代的 影响。

IDENTIFICATION AND USE: Lithium amide is a white crystalline powder which is slightly soluble in ethanol, liquid ammonia and insoluble in anhydrous ether, benzene , xylene and toluene. It is used in Claisen condensations; alkylation of nitriles and ketones; synthesis of ethynyl compounds, and acetylenic carbinols. It is used in organic synthesis, including antihistamines and other pharmaceuticals. HUMAN EXPOSURE AND TOXICITY: Lithium amide is a powerful irritant to skin, eyes, and mucous membrane. ANIMAL STUDIES: The most prominent symptoms of acute lithium poisoning in animals when given lithium either by mouth or iv are anorexia, nausea, vomiting, diarrhea and salivation with loss of weight, dehydration and fall of body temperature. Effects on CNS are manifested by muscular weakness, hyperirritability, stupor and convulsions; on the heart by EKG changes with auricular standstill or fibrillation; on the kidneys by oliguria, a rise in blood protein nitrogen and degenerative changes in tubular epithelium. Chronic renal failure was induced by administering lithium orally to 14 newborn rats. Seven rats were treated for 8 weeks followed by 8 weeks without lithium (group Li/C) and seven for 16 weeks (group Li/Li). Plasma urea and renal concentrating ability were measured, and one kidney fixed by vascular perfusion. Mean glomerular volume as well as volumes of individual glomeruli were estimated. In addition, the structural integrity between the glomerulus and the proximal tubule was investigated on serial sections. No sclerotic glomeruli were present. Only 37.6 and 27.9% of the glomeruli in the Li/C and Li/Li groups, respectively, were connected to a normal proximal tubule, and most remaining glomeruli were atubular. The mean glomerular volume was unchanged in the Li/C group and reduced by 40% in the Li/Li group. The intraindividual variation in glomerular volume was about 10-fold larger in the lithium-treated groups than in controls. The glomeruli connected to normal proximal tubules had the largest volumes, and hypertrophied glomeruli were encountered more frequently in the Li/C group than in the Li/Li group. There was a significant positive correlation between the plasma urea and the fraction of glomeruli that were not connected to normal proximal tubules. While there has been some indication of adverse effects on fetuses following lithium treatment, none was observed in rats, rabbits or primates. This dose to rats was sufficient to produce maternal toxicity and effects on the pups of treated, lactating dams.

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 副作用

神经毒素 - 其他中枢神经系统神经毒素 肾毒素 - 该化学物质在工作环境中可能对肾脏有毒。 皮肤毒素 - 皮肤烧伤。 中毒性肺炎 - 由于吸入金属烟雾或有毒气体和蒸气引起的肺部炎症。

Neurotoxin - Other CNS neurotoxin Nephrotoxin - The chemical is potentially toxic to the kidneys in the occupational setting. Dermatotoxin - Skin burns. Toxic Pneumonitis - Inflammation of the lungs induced by inhalation of metal fumes or toxic gases and vapors.

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

毒理性

• 解毒与急救

基本治疗：建立专利气道（如需要，使用口咽或鼻咽气道）。如有必要，进行吸痰。观察呼吸不足的迹象，如有必要，协助通气。通过非重复呼吸面罩以10至15升/分钟的速度给予氧气。监测肺水肿，如有必要，进行治疗……监测休克，如有必要，进行治疗……预见并治疗癫痫发作……对于眼睛污染，立即用水冲洗眼睛。在治疗期间，用0.9%的生理盐水（NS）连续冲洗每只眼睛……不要使用催吐剂。对于摄入，如果患者能够吞咽、有强烈的干呕反射且不流口水，则用水冲洗口腔，并给予5毫升/千克，最多200毫升的水进行稀释……在去污后，用干燥的无菌敷料覆盖皮肤烧伤……/锂及其相关化合物/

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... Monitor for shock and treat if necessary ... Anticipate seizures and treat if necessary ... For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during treatment ... Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... Cover skin burns with dry sterile dressings after decontamination ... /Lithium and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

高级治疗：对于昏迷、严重肺水肿或严重呼吸困难的病人，考虑进行口咽或鼻咽气管插管以控制气道。使用气囊阀面罩装置的正压通气技术可能有益。考虑对肺水肿进行药物治疗... 监测心率和必要时治疗心律失常... 开始静脉输注D5W/SRP：“保持开放”，最低流速/。如果出现低血容量的迹象，使用0.9%盐水（NS）或乳酸林格氏液（LR）。对于伴有低血容量迹象的低血压，谨慎给予液体。如果病人在正常血容量时出现低血压，考虑使用血管加压药。注意液体过载的迹象... 使用地西泮或劳拉西泮治疗癫痫... 使用丙美卡因氢氯化物协助眼部冲洗... /锂及其相关化合物/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Consider drug therapy for pulmonary edema ... Monitor cardiac rhythm and treat arrhythmias if necessary ... Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... Treat seizures with diazepam or lorazepam ... Use proparacaine hydrochloride to assist eye irrigation ... /Lithium and related compounds/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 人类毒性摘录

症状和体征/ 在治疗初期阶段可能会出现急性中毒，但在长期治疗期间的任何时间点或急性过量后也可能发生。当血浆水平在1.5到2.5毫摩尔/升之间时，毒性迹象包括食欲不振、口干、恶心、呕吐、腹泻、手颤、肌肉无力、口渴、白细胞增多以及注意力和记忆障碍（特别是在老年人中）。这些现象通常出现在治疗初期，并通常在治疗继续时消失，除了手颤。在老年人中，可能会出现可逆的谵妄状态，表现为混乱、不安和共济失调。当血浆水平超过2.5毫摩尔/升时，会出现严重的毒性症状；肌肉颤动、肌肉收缩、反射亢进和肌张力增高、嗜睡、混乱、有时出现癫痫样发作、低血压、昏迷、虚脱。无论血浆水平如何，心电图（ECG）和脑电图（EEG）都可能发生变化，症状包括多尿和多饮，罕见肾源性尿崩症，腿部溃疡，痤疮和银屑病的加重，暂时性高血糖，瘙痒和金属味。在大约5%的病例中，会出现（通常是可逆的）甲状腺功能减退症。/锂+/

/SIGNS AND SYMPTOMS/ Acute intoxication can occur in the initial phase in a course of therapy, but also at any point of time during long-lasting treatment or after an acute overdose. At plasma levels between 1.5 and 2.5 mmol/L, signs of toxicity include anorexia, dry mouth, nausea, vomiting, diarrhea, tremor of the hands, faintness of musculature, thirst, leucocytosis, and concentration and memory disturbances (especially with older people). These phenomena are often seen in the initial phase of a course of treatment and usually disappear when treatment continues, except with the tremor of the hands. In elderly people, reversible delirious conditions can occur with confusion, restlessness, and ataxia. At plasma levels above 2.5 mmol/L, serious toxic symptoms occur; fasciculations, muscle contractions, hyperreflexia and hypertonia, drowsiness, confusion, sometimes epileptiform insults, hypotension, coma, collapse. Independent of the plasma level, changes can occur in the ECG and in the EEC, with symptoms such as polyuria and polydipsia, seldom nephrogenic diabetes insipidus, ulcers of the leg, enhancement of acne and psoriasis, transient hyperglycemia, pruritus, and a metal taste. In about 5% of the cases, a (usually reversible) hypothyroidia develops. /Li+/

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

所有可溶性锂化合物都很容易从胃肠道以及从皮下、肌肉和腹腔内储存库中被吸收，在给药后几分钟内出现在组织液和器官中。/可溶性锂化合物/

All sol lithium cmpd are readily absorbed from GI tract as well as from sc, im, and ip depots, appearing in tissue fluids and organs within a few min of admin. /Sol lithium cmpd/

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

Li+很容易被吸收，几乎完全从胃肠道吸收。在大约8小时内完成吸收，口服剂量后2到4小时血浆中达到峰值浓度。碳酸锂的缓释制剂提供较慢的吸收速率，从而最小化早期血浆中离子浓度的峰值。然而，吸收可能会有所变化，并且降低肠症状的发生率可能会增加。Li+最初分布在细胞外液中，然后逐渐在各种组织中积累。穿过细胞膜的浓度梯度远小于Na+和K+。最终分布体积（0.7到0.9 L/kg）接近总体水，远低于大多数其他亲脂性和蛋白结合的精神药物。穿过血脑屏障的速度很慢，当达到稳态时，脑脊液中Li+的浓度约为血浆中浓度的40%到50%。该离子不会显著结合血浆蛋白。

Li+ is absorbed readily and almost completely from the GI tract. Complete absorption occurs in about 8 hr, with peak concn in plasma occurring 2 to 4 hr after an oral dose. Slow-release preparations of lithium carbonate provide a slower rate of absorption and thereby minimize early peaks in plasma concn of the ion. However, absorption can be variable, and the incidence of lower intestinal tract symptoms may be incr. Li+ initially is distributed in the extracellular fluid and then gradually accumulates in various tissues. The concentration gradient across plasma membranes is much smaller than those for Na+ and K+. The final volume of distribution (0.7 to 0.9 L/kg) approaches that of total body water and is much lower than that of most other psychotropic agents, which are lipophilic and protein-bound. Passage through the blood-brain barrier is slow, and when a steady state is achieved, the concn of Li+ in the cerebrospinal fluid is about 40% to 50% of the concn in plasma. The ion does not bind appreciably to plasma proteins. /Li+/

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

LI+ 遵守口服给药后人体的双室模型动力学。其分布和消除动力学与伴随的阴离子无关，终末消除半衰期约为22小时。

LI+ OBEYS TWO-COMPARTMENT MODEL KINETICS AFTER ORAL DOSES TO HUMAN SUBJECTS. ITS DISTRIBUTION & ELIMINATION KINETICS ARE INDEPENDENT OF THE ACCOMPANYING ANION & THE TERMINAL ELIMINATION T/2 IS ABOUT 22 HR. /Li+/

来源:Hazardous Substances Data Bank (HSDB)

吸收、分配和排泄

大约95%的单剂量锂+通过尿液排出。急性剂量的三分之一到三分之二在排出的最初6到12小时期间被排泄，随后在接下来的10到14天内缓慢排泄。消除半衰期平均为20到24小时。随着反复给药，锂+的排泄在前5到6天内增加，直到摄入和排泄之间达到稳态。当锂+治疗停止时，首先有一个快速的肾脏排泄期，然后是一个慢性的10到14天的排泄期。由于过滤的锂+中有80%被近端肾小管重吸收，肾脏对锂+的清除率约为肌酐的20%，在15到30毫升/分钟之间。这在老年患者中略低（10到15毫升/分钟）。/锂+/

Approximately 95% of a single dose of Li+ is eliminated in the urine. From one- to two-thirds of an acute dose is excreted during a 6- to 12-hr initial phase of excretion, followed by slow excretion over the next 10 to 14 days. The elimination half-life averages 20 to 24 hr. With repeated admin, Li+ excretion incr during the first 5 to 6 days until a steady state is reached between ingestion and excretion. When therapy with Li+ is stopped, there is a rapid phase of renal excretion followed by a slow 10- to 14-day phase. Since 80% of the filtered Li+ is reabsorbed by the proximal renal tubules, clearance of Li+ by the kidney is about 20% of that for creatinine, ranging between 15 and 30 mL/min. This is somewhat lower in elderly patients (10 to 15 mL/min). /Li+/

来源:Hazardous Substances Data Bank (HSDB)

反应信息

• 作为反应物：
  描述：

  lithium amide 以 neat (no solvent) 为溶剂， 生成 lithium imide
  参考文献：
  名称：

  通过机械活化将酰胺化锂增强为酰亚胺化锂。

  摘要：

  研究了在高能球磨和不进行高能球磨的条件下，酰胺锂（LiNH2）分解为酰亚胺锂（Li2NH）和氨（NH3）的方法，为确定提高酰胺锂和氢化锂的氢吸收/释放方法奠定了基础。混合物。广泛的分析仪器被用来提供机械活化作用的明确证据。结果表明，球磨将LiNH2分解的起始温度从120摄氏度降低到了室温。通过球磨增强的分解归因于与纳米微晶形成有关的机械活化，减小的粒度，增加的表面积和降低的活化能。机械激活越多，则可以进一步增强LiNH2的分解。还发现在不进行球磨的情况下分解LiNH2的活化能为243.98 kJ / mol，在室温下球磨45分钟后降低到222.20 kJ / mol，在球化后进一步降低到138.05 kJ / mol。研磨180分钟 LiNH 2分解后期的等温分解速率是通过NH 3通过Li 2 NH层的扩散来控制的。

  DOI：

  10.1021/jp060181c
• 作为产物：
  描述：

  氨 、 lithium 以 neat (no solvent, gas phase) 为溶剂， 生成 lithium amide
  参考文献：
  名称：

  First Synthesis and Structural Determination of a Monomeric, Unsolvated Lithium Amide, LiNH₂

  摘要：

  Alkali metal amides typically aggregate in solution and the solid phase, and even in the gas phase. In addition, even in the few known monomeric structures, the coordination number of the alkali metal is raised by binding of Lewis-basic solvent molecules, with concomitant changes in structure. In contrast, the simplest lithium amide LiNH2 has never been made in a monomeric form, even though its structure has been theoretically predicted several times. Here, the first experimental structural data for a monomeric, unsolvated lithium amide are determined using a combination of gas-phase synthesis and millimeter/submillimeter-wave spectroscopy. All data point to a planar structure for LiNH2. The r(o) structure of LiNH2 has a Li-N distance of 1.736(3) Angstrom, an N-H distance of 1.022(3) Angstrom, and a H-N-H angle of 106.9(1)degrees. These results are compared with theoretical predictions for LiNH2, and experimental data for oligomeric, solid-phase samples, which could not resolve the question of whether LiNH2 is planar or not. In addition, comparisons are made with revised gas-phase and solid-phase data and calculated structures of NaNH2.

  DOI：

  10.1021/ja003422h
• 作为试剂：
  描述：

  2,5-二氯苯甲腈 、 4-氟苯胺 在 氨 、 sodium amide 、 lithium amide 作用下， 以 乙醚 为溶剂， 反应 4.5h， 以33%的产率得到6-amino-8-chloro-2-fluorophenanthridine
  参考文献：
  名称：

  A single step synthesis of 6-aminophenanthridines from anilines and 2-chlorobenzonitriles

  摘要：

  Biologically active 6-aminophenanthridines were prepared in a single step procedure: Metal amides in liquid ammonia promoted the condensation of anilines with 2-chloro-benzonitriles. 6-Aminophenanthridines were isolated in moderate yield. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2004.03.062

文献信息

• Novel Stibano Amines: Synthesis and Reactivity towards Group 13 Element Organics
  作者：Benjamin Ringler、Carsten von Hänisch

  DOI：10.1002/zaac.201500787

  日期：2016.2

  and nitrogen containing interpnictogen compounds are described. Using tBu2SbCl as reagent, a tert-butyl-substituted stibano amine tBu2SbN(H)tBu (1), an isopropyl-substituted interpnictogen tBu2SbN(H)iPr (2), and a primary stibano amine tBu2SbNH2 (3) are obtained. Condensation of compound 3 leads to compound (tBu2Sb)2NH (4) with elimination of ammonia. All compounds were characterized by 1H, 13C, 15N NMR

  在本文中，描述了含锑和氮的interpnictogen 化合物的合成。以tBu2SbCl为试剂，得到叔丁基取代的stibano胺tBu2SbN(H)tBu(1)、异丙基取代的interpnictogen tBu2SbN(H)iPr(2)和stibano伯胺tBu2SbNH2(3)。化合物 3 缩合生成化合物 (tBu2Sb)2NH (4)，同时消除氨。所有化合物均通过 1H、13C、15N NMR 光谱、质谱和 IR 光谱进行表征。这些interpnictogens 代表了MOVPE 过程的一类新的单一来源的前体。伯胺 3 与 AlEt3 和 GaEt3 反应形成以前未知的 stibane 取代的 [tBu2SbN(H)MEt2]2 环化合物 [M = Al (5), M = Ga (6)]，通过不同的光谱方法对其进行表征。而且，
• Alkali ion conducting plastic crystals
  申请人：Angell Charles Austen

  公开号：US10497970B2

  公开（公告）日：2019-12-03

  A solid electrolyte represented by general formula LiySiRx(MO4), where x is an integer from 1 to 3 inclusive, y=4−x, each R present is independently C1-C3 alkyl or C1-C3 alkoxy, and M is sulfur, selenium, or tellurium. Methods of making the solid electrolyte include combining a phenylsilane and a first acid to yield mixture including benzene and a second acid, and combining at least one of an alkali halide, and alkali amide, and an alkali alkoxide with the second acid to yield a product d represented by general formula LiySiRx(MO4)y. The second acid may be in the form of a liquid or a solid. The phenylsilane includes at least one C1-C3 alkyl substituent or at least one C1-C3 alkoxy substituent, and the first acid includes at least one of sulfuric acid, selenic acid, and telluric acid.

  固体电解质的通用公式表示为 LiySiRx(MO4)，其中 x 是从 1 到 3 的整数，y=4-x，每个 R 独立地代表 C1-C3 烷基或 C1-C3 烷氧基，M 是硫、硒或碲。制造这种固体电解质的方法包括将苯基硅烷和第一种酸混合，产生包括苯和第二种酸的混合物，以及将至少一种碱金属卤化物、碱金属酰胺和碱金属醇盐与第二种酸混合，产生代表通用公式 LiySiRx(MO4)y 的产品 d。第二种酸可以是液态或固态。苯基硅烷包括至少一个 C1-C3 烷基取代基或至少一个 C1-C3 烷氧基取代基，第一种酸包括至少一种硫酸、硒酸和碲酸。
• Synthetic and Mechanistic Investigations of Trimethylsilyl-Substituted Triamidoamine Complexes of Tantalum That Contain Metal−Ligand Multiple Bonds
  作者：Joel S. Freundlich、Richard R. Schrock、William M. Davis

  DOI：10.1021/ja953826n

  日期：1996.1.1

  −35 °C to afford the phosphinidene complexes [N3N]TaPR (R = Me, n-Bu, SiMe3, SiMe2Ph). [N3N]TaCl2 reacts with 2 equiv of LiN(H)R (R = H, CMe3, Ph) to produce 1 equiv of RNH2 and imido complexes [N3N]TaNR and with 2 equiv of benzylmagnesium chloride or ((trimethylsilyl)methyl)lithium to afford the alkylidene complexes [N3N]TaCHR (R = Ph or SiMe3). The ethylene complex [N3N]Ta(C2H4) is formed quantitatively

  [N3N]TaPPh ([N3N]3- = [(Me3SiNCH2CH2)3N]3-) 与过量的锂金属在四氢呋喃中反应生成“[N3N]TaPLi”，根据 NMR 研究和与 RX 在 -35° 的反应判断C 得到膦化物复合物 [N3N]TaPR (R = Me, n-Bu, SiMe3, SiMe2Ph)。[N3N]TaCl2 与 2 当量的 LiN(H)R (R = H, CMe3, Ph) 反应生成 1 当量的 RNH2 和亚胺配合物 [N3N]TaNR，并与 2 当量的苄基氯化镁或（（三甲基甲硅烷基）甲基）锂以提供亚烷基配合物 [N3N]TaCHR（R = Ph 或 SiMe3）。将 2 当量的氯化乙基镁加入 [N3N]TaCl2 中，即可定量形成乙烯络合物 [N3N]Ta(C2H4)。[N3N]Ta(C2H4) 在溶液中在室温下经过几天的时间以一级方式分解，得到一种复合物，其中 TREN
• Synthesis of Rhodium and Iridium Complexes Supported by Bis(indolylphosphino)silyl Pincer Ligation: Competitive N–H and C–H Bond Activation by an Ir(I) Species
  作者：Helia Hollenhorst、Robert McDonald、Michael Ferguson、Laura Turculet

  DOI：10.1021/acs.organomet.1c00114

  日期：2021.8.23

  The synthesis of five-coordinate amido hydride PSiP pincer complexes of both RhIII and IrIII was pursued. The preparation of such complexes by a salt metathesis route was initially targeted to assess the synthetic viability of such species. Isolable anilido hydride complexes of both Rh and Ir proved accessible, and rare examples of thermally robust Ir alkylamido hydride complexes were found to be viable

  进行了 Rh III和 Ir III的五配位酰氨基氢化物 PSiP 钳形配合物的合成。通过盐复分解途径制备此类复合物最初旨在评估此类物种的合成可行性。Rh 和 Ir 的可分离的苯胺氢化物复合物被证明是可获得的，并且发现热稳定的 Ir 烷基酰胺氢化物复合物的罕见例子是可行的合成目标。还进行了通过 N-H 氧化加成制备酰氨基氢化物的研究。为此，研究了配位不饱和 ( i Pr-PSiP Ind )M I (M = Rh, Ir) 物种的产生。( i Pr-PSiP Ind的脱卤化氢)RhH(Cl) ( 1 ) 在 N 2 下得到可分离的复合物 [( i Pr-PSiP Ind )Rh] 2 (μ-N 2 ) ( 8a )。虽然可以置换N 2配体以提供 ( i Pr-PSiP Ind )RhL (L = PMe 3 , DMAP, H 2 NPh)，但证明此类 Rh I物质对苯胺的 N-H 氧化加成没有反应。(
• Amidoboranes of rubidium and caesium: the last missing members of the alkali metal amidoborane family
  作者：Rafał Owarzany、Tomasz Jaroń、Piotr J. Leszczyński、Karol J. Fijalkowski、Wojciech Grochala

  DOI：10.1039/c7dt03590j

  日期：——

  characterization of two ammonia borane derivatives: rubidium amidoborane (RbNH2BH3) and caesium amidoborane (CsNH2BH3). Both compounds undergo solid–solid phase transition upon heating and then evolve pure hydrogen at temperatures lower than 125 °C. The phase transition is clearly seen in the Raman spectra. We present crystal structures of both low- and high-temperature forms of the title compounds which were solved

  我们报告了两种氨硼烷衍生物：and硼烷character（RbNH 2 BH 3）和am硼烷铯（CsNH 2 BH 3）的合成和理化特性。两种化合物在加热时都会经历固-固相变，然后在低于125°C的温度下释放出纯氢。在拉曼光谱中可以清楚地看到相变。我们介绍了低温和高温形式的标题化合物的晶体结构，这些结构是根据粉末X射线数据解决的。