2,4,6-tris(n-butylamino)-1,3,5-triazine | 16268-97-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 2,4,6-tris(n-butylamino)-1,3,5-triazine
• 英文别名: N²,N⁴,N⁶-tributyl-1,3,5-triazine-2,4,6-triamine；tributylmelamine；2,4,6-tris(butylamino)-1,3,5-triazine；TBTAT；N²,N⁴,N⁶-tributyl-[1,3,5]triazine-2,4,6-triyltriamine；N²,N⁴,N⁶-Tributyl-[1,3,5]triazin-2,4,6-triyltriamin；2-N,4-N,6-N-tributyl-1,3,5-triazine-2,4,6-triamine
• CAS: 16268-97-6
• 化学式: C₁₅H₃₀N₆
• 分子量: 294.443
• InChiKey: HCDRIXGPYLLIQV-UHFFFAOYSA-N

物化性质

• 沸点：
  450.3±28.0 °C(Predicted)
• 密度：
  1.066±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  74.8
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,4,6-tris(n-butylamino)-1,3,5-triazine 、 双三氟甲烷磺酰亚胺 以 甲醇 为溶剂， 反应 0.5h， 生成 N,N',N''-tributyl-[1,3,5]triazine-2,4,6-triamine bis(trifluoromethanesulfonyl)imide salt
  参考文献：
  名称：

  EP2078715

  摘要：

  公开号：
• 作为产物：
  描述：

  2,4-bis(butylamino)-6-chloro-1,3,5-triazine 、 正丁胺 以 various solvent(s) 为溶剂， 生成 2,4,6-tris(n-butylamino)-1,3,5-triazine
  参考文献：
  名称：

  Kinetic studies on the Reaction of Cyanuric Chloride with Amines

  摘要：

  The individual steps in the reactions of cyanuric chloride with n-butyl amine in N-methyl pyrrolidone (NMP) and with morpholine in isopropanol (i-PrOH) were followed kinetically. The ratio of the exchange rates of the first, the second and the third chlorine atom was unexpectedly high in both cases. The reactions of n-butylamino dichlorotriazine with several amines were studied kinetically both in NMP and in i-PrOH. Linear free-energy relationships exist both between our values in NMP and in isopropanol and between our values and reaction rates of p-nitro fluorobenzene with the corresponding amines (in DMSO) determined by Suhr.

  DOI：

  10.1002/prac.19953370128

文献信息

• In situ generated and stabilized Pd nanoparticles by N²,N⁴,N⁶-tridodecyl-1,3,5-triazine-2,4,6-triamine (TDTAT) as a reactive and efficient catalyst for the Suzuki–Miyaura reaction in water
  作者：Nasser Iranpoor、Sajjad Rahimi、Farhad Panahi

  DOI：10.1039/c5ra24120k

  日期：——

  The Suzuki–Miyaura coupling reaction was efficiently catalyzed by the in situ generated and stabilized Pd nanoparticles employing TDTAT in water.

  Suzuki–Miyaura 偶联反应在水中通过 in situ 生成和稳定的 Pd 纳米颗粒，利用 TDTAT 有效催化。
• CYANOETHYLMELAMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME
  申请人：NISSAN CHEMICAL INDUSTRIES, LIMITED

  公开号：EP0945446A1

  公开（公告）日：1999-09-29

  The present invention relates to a cyanoethylmelamine derivatives of the formula I: wherein 1 to 5 of the substituents X' to X6 represent a cyanoethyl group and at least one remaining group represents a C1-20 alkyl group, a C2-20 alkenyl group (said alkyl or alkenyl group may optionally have an alicyclic group or a phenyl group in its structure), a C5-6 cycloalkyl group or a phenyl group, or two of the substituent groups bonded to the same nitrogen atom together may form an alkylene chain having 2 to 7 carbon atoms, and the remaining substituent or substituents represents a hydrogen atom}. The production of cyanoethylmelamine derivatives can be obtained at high yield by reacting N-substituted melamine derivatives with acrylonitrile or reacting mono- or di-halogeno-N-substituted triazine derivative with aminopropionitrile. The compounds of the formula (I) are useful compounds as intermediates for fine chemicals such as agricultural chemicals, medicines, dye stuffs, paints, etc. and as crosslinking intermediates for resins.

  本发明涉及一种公式I的氰乙基三聚氰胺衍生物：其中取代基X'至X6中的1至5个代表氰乙基基团，至少一个剩余基团代表C1-20烷基基团，C2-20烯基基团（该烷基或烯基基团的结构中可能含有环烷基或苯基），C5-6环烷基基团或苯基，或两个结合到同一氮原子的取代基团可共同形成具有2至7个碳原子的烷基链，其余的取代基或取代基团代表氢原子}。通过将N-取代三聚氰胺衍生物与丙烯腈反应或将单取代或双卤代N-取代三嗪衍生物与氨基丙腈反应，可以高产率地获得氰乙基三聚氰胺衍生物。公式（I）的化合物是作为农药、药物、染料、涂料等精细化学品的中间体以及树脂的交联中间体的有用化合物。
• Method of alkylating triazine derivatives
  申请人：Nissan Chemical Industries, Ltd.

  公开号：US06130332A1

  公开（公告）日：2000-10-10

  The object of the present invention is to provide a method for producing substituted-1,3,5-triazine derivatives at high yield, in which at least one of carbon atoms in the ring thereof is substituted by a secondary amine group having at leat one of alkyl groups. The method of the present invention is a method for alkylation of 1,3,5-triazine derivatives, characterized by reacting 1,3,5-triazine derivatives (melamines, melamine derivatives, various kinds of guanaminde derivatives, etc.) which has at least one or more amino groups or mono-substituted amino groups on carbon atom of the ring thereof, with aldehydes or ketones alcohols in the presence of a catalyst of a metal of group VII and/or group VIII in the periodic table and a hydrogen-containing gas to alkylate said at least one of amino groups or mono-substituted amino groups. These derivatives are widely used as intermediates of fine chemicals such as agricultural chemicals, medications, dyestuffs, paints and the like and are widely used resin materials and as flame-retardant materials.

  本发明的目的是提供一种高产率生产取代-1,3,5-三嗪衍生物的方法，其中该环中的至少一个碳原子被具有至少一个烷基的二级胺基所取代。本发明的方法是一种1,3,5-三嗪衍生物的烷基化方法，其特征在于，在周期表中的七族和/或八族金属催化剂和含氢气体的存在下，将至少具有一个或多个氨基或环上单取代氨基的1,3,5-三嗪衍生物（三聚氰胺，三聚氰胺衍生物，各种脲衍生物等）与醛或酮醇反应，以烷基化所述至少一个氨基或单取代氨基。这些衍生物广泛用作农业化学品、药品、染料、涂料等精细化学品的中间体，以及广泛用于树脂材料和阻燃材料。
• Method of alkylating of triazine derivatives
  申请人：Nissan Chemical Industries, Ltd.

  公开号：US05792867A1

  公开（公告）日：1998-08-11

  A method for alkylation of at least one or more amino groups or mono-substituted amino groups, each on a carbon atom of a triazine ring of 1,3,5-triazine derivatives (melamine, melamine derivatives and various kinds of guanamine derivatives and the like), which includes reacting the 1,3,5-triazine derivatives having at least one or more amino groups or mono-substituted amino groups with alcohols in the presence of a catalyst of a metal of group VII and/or group VIII in the periodic table. The object of the invention is to provide a method for alkylation of 1,3,5-triazine derivatives, which includes alkylating amino groups or mono-substituted amino groups in carbon atoms of a 1,3,5-triazine ring, whereby substituted 1,3,5-triazine derivatives which are a group of useful compounds and which are widely used as intermediates of fine chemicals such as agricultural chemicals, medications, dye-stuffs, paints and the like, as resin materials and as flame-retardant materials can be easily produced in high yields.

  一种用于烷基化1,3,5-三嗪衍生物（三聚氰胺、三聚氰胺衍生物、各种脲衍生物等）中至少一个或多个氨基或单取代氨基的碳原子的方法，包括在周期表中的第VII和/或第VIII族金属催化剂的存在下，将具有至少一个或多个氨基或单取代氨基的1,3,5-三嗪衍生物与醇反应。该发明的目的是提供一种烷基化1,3,5-三嗪衍生物的方法，其中包括在1,3,5-三嗪环的碳原子上烷基化氨基或单取代氨基，从而可以高产地轻松制备出取代的1,3,5-三嗪衍生物，这些衍生物是一类有用的化合物，广泛用于农药、药物、染料、涂料等精细化学品的中间体，以及树脂材料和阻燃材料。
• Method for modifying melamine derivatives
  申请人：Nissan Chemical Industries, Ltd.

  公开号：US06307046B1

  公开（公告）日：2001-10-23

  The present invention provides a method for modifying melamine derivatives that can produce N-substituted melamine derivatives by introducing a substituent group to melamine or N-substituted melamine derivatives. The method is characterized by heating melamine or an N-substituted melamine derivative and an alcohol in the presence of a mixed catalyst comprising a hydrogenation catalyst and a dehydrogenation catalyst and hydrogen to allow reaction or heating melamine or an N-substituted melamine derivative and an alcohol in the presence of a hydrogenation catalyst and hydrogen with addition/coexistence of a metal to allow reaction. The compound groups obtained by introducing a substituent group to the amino group of melamine derivative with an alcohol by the method of the present invention can be used widely as intermediates of fine chemicals such as various agricultural chemicals, medicines, dyes, paints, etc. and as various resin materials and flame retardant materials.

  本发明提供了一种改性三聚氰胺衍生物的方法，该方法可以通过向三聚氰胺或N-取代三聚氰胺衍生物引入取代基团来产生N-取代三聚氰胺衍生物。该方法的特点是，在氢化催化剂和脱氢催化剂的混合催化剂和氢气的存在下，加热三聚氰胺或N-取代三聚氰胺衍生物和醇以允许反应，或在氢化催化剂和氢气的存在下，加热三聚氰胺或N-取代三聚氰胺衍生物和醇，并添加/共存于金属以允许反应。通过本发明方法将醇引入到三聚氰胺衍生物的氨基中，得到的化合物基团可以广泛用作各种农药、药品、染料、涂料等精细化学品的中间体，以及各种树脂材料和阻燃材料。