溴(三乙基)铅 | 41141-89-3

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 中文名称: 溴(三乙基)铅
• 英文名称: triethyllead bromide
• 英文别名: triethyl lead (1+); bromide；Triaethyl-blei(1+); Bromid；Triaethyl-brom-plumban；Triaethylbleibromid；Triethylbleibromid；Plumbane, bromotriethyl-；bromo(triethyl)plumbane
• CAS: 41141-89-3
• 化学式: C₆H₁₅BrPb
• 分子量: 374.289
• InChiKey: RLEMIFPVSKAYPE-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  3.39
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2931900090

SDS

Version 1.4
Regulation (EC) No 1907/2006

---

1 - Product and Company Information

---

Product Name BROMOTRIETHYLLEAD - 50 MG

---

2 - Hazards Identification

---

SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
May cause harm to the unborn child. Also very toxic by inhalation,
in contact with skin and if swallowed. Danger of cumulative
effects. Very toxic to aquatic organisms, may cause long-term
adverse effects in the aquatic environment. Possible risk of
impaired fertility.
Repr. Cat.1 Repr. Cat.3

---

3 - Composition/Information on Ingredients

---

Product Name CAS # EC no Annex I
Index Number
BROMOTRIETHYLLEAD 41141-89-3 None 082-002-00-1
Formula C6H15BrPb
Molecular Weight 374,2900 AMU

---

4 - First Aid Measures

---

AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
ALDRICH www.molbase.com
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.

---

5 - Fire Fighting Measures

---

EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.

---

6 - Accidental Release Measures

---

PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.

---

7 - Handling and Storage

---

HANDLING
Directions for Safe Handling: Do not breathe dust. Do not get in
eyes, on skin, on clothing. Avoid prolonged or repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed.

---

8 - Exposure Controls / Personal Protection

---

ENGINEERING CONTROLS
Safety shower and eye bath. Use only in a chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Use respirators and components tested and
approved under appropriate government standards such as NIOSH (US)
or CEN (EU). Where risk assessment shows air-purifying respirators
are appropriate use a full-face particle respirator type N100 (US)
or type P3 (EN 143) respirator cartridges as a backup to
engineering controls. If the respirator is the sole means of
protection, use a full-face supplied air respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.

---

9 - Physical and Chemical Properties
ALDRICH www.molbase.com

---

Appearance Physical State: Solid
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A

---

10 - Stability and Reactivity

---

STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents, Strong acids.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Nature of decomposition products
not known.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur

---

11 - Toxicological Information

---

SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
Exposure can cause: Anemia. Lead salts have been reported to
cross the placenta and to induce embryo- and feto- mortality.
They also have teratogenic effect in some animal species. No
teratogenic effects have been reported with exposure to
organometallic lead compounds. Adverse effects of lead on human
reproduction, embryonic and fetal development, and postnatal
(e.g., mental) development have been reported. Excessive
exposure can affect blood, nervous, and digestive systems. The
synthesis of hemoglobin is inhibited and results in anemia. If
left untreated, neuromuscular dysfunction, possible paralysis,
and encephalopathy can result. Additional symptoms of
overexposure include: joint and muscle pain, weakness of the
extensor muscles (frequently the hand and wrist), headache,
ALDRICH www.molbase.com
dizziness, abdominal pain, diarrhea, constipation, nausea,
vomiting, blue line on the gums, insomnia, and metallic taste.
High body levels produce increased cerebrospinal pressure, brain
damage, and stupor leading to coma and often death.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be fatal if absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be fatal if inhaled.
Ingestion: May be fatal if swallowed.
TARGET ORGAN INFORMATION
Nerves. Blood. Kidneys. Female reproductive system. Male
reproductive system.
CHRONIC EXPOSURE - TERATOGEN
Result: May cause congenital malformation in the fetus.
CHRONIC EXPOSURE - REPRODUCTIVE HAZARD
Result: May cause reproductive disorders.
CMR CAT.: Carc. Cat.3

---

12 - Ecological Information

---

No data available.

---

13 - Disposal Considerations

---

SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Observe all federal, state, and local
environmental regulations.

---

14 - Transport Information

---

RID/ADR
UN#: 3467
Class: 6.1
PG: II
Proper Shipping Name: Organometallic compound, toxic,
solid, n.o.s.
IMDG
UN#: 3467
Class: 6.1
PG: II
Proper Shipping Name: Organometallic compound, toxic,
solid, n.o.s.
Marine Pollutant: Yes
Severe Marine Pollutant: No
Technical Name: Required
IATA
UN#: 3467
Class: 6.1
PG: II
Proper Shipping Name: Organometallic compound, toxic,
solid, n.o.s.
ALDRICH www.molbase.com
Inhalation Packing Group I: No
Technical Name: Required

---

15 - Regulatory Information

---

CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 082-002-00-1
NOTA: A,E, 1
INDICATION OF DANGER: T+-N
Very toxic. Dangerous for the environment.
R-PHRASES: 61-26/27/28-33-50/53-62
May cause harm to the unborn child. Also very toxic by
inhalation, in contact with skin and if swallowed. Danger of
cumulative effects. Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment. Possible
risk of impaired fertility.
S-PHRASES: 53-45-60-61
Restricted to professional users. Attention - Avoid exposure -
obtain special instructions before use. In case of accident or
if you feel unwell, seek medical advice immediately (show the
label where possible). This material and its container must be
disposed of as hazardous waste. Avoid release to the
environment. Refer to special instructions/safety data sheets.
Caution: Substance not yet fully tested (EU).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
Self-Classification

---

16 - Other Information

---

WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2010 Co. License granted to make
unlimitedpaper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
ALDRICH www.molbase.com

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  溴(三乙基)铅 在 氢氧化钾 、 乙醚 作用下， 生成 triethyl lead (1+), hydroxide
  参考文献：
  名称：

  Krause; Pohland, Chemische Berichte, 1922, vol. 55, p. 1289 Anm.1

  摘要：

  DOI：
• 作为产物：
  描述：

  四乙基铅 在 乙醚 、 氢溴酸 作用下， 生成 溴(三乙基)铅
  参考文献：
  名称：

  Hein; Klein, Chemische Berichte, 1938, vol. 71, p. 2382

  摘要：

  DOI：

文献信息

• Norbornyl Cations of Group 14 Elements
  作者：Thomas Müller、Christian Bauch、Markus Ostermeier、Michael Bolte、Norbert Auner

  DOI：10.1021/ja021234g

  日期：2003.2.1

  (4i)) and the small J coupling constants between the element and the remote vinyl carbons in the case of 4h and 4i (J(CSn) = 26 Hz, J(CPb) = 16 Hz) give experimental evidence for the intramolecular interaction and the charge transfer between the positively charged element and the remote C=C double bond. The experimental results are supported by quantum mechanical calculations of structures, energies, and

  14 族元素 Si --> Pb 的降冰片基阳离子已从取代的 3-环戊烯甲基前体通过将瞬时阳离子分子内加成到 3-环戊烯甲基取代基的 C=C 双键（pi-路线到降冰片基阳离子）合成。降冰片基阳离子 4a (E = Si, R = Me), 4e (E = Si, R = Et), 4f (E = Si, R = Bu), 4g (E = Ge, R = Bu), 4h (E = Sn, R = Bu) 和 4i (E = Pb, R = Et) 已通过其特征 NMR 化学位移 (4a,e,f, delta((29)Si) = 80-87, delta((( 13)C)(CH=) = 149.6-150.6; 4g, delta((13)C)(CH=) = 144.8; 4h, delta((119)Sn) = 334, delta((13)C)(CH =) = 141.5; 4i, delta((207)Pb)
• Trifluormethylsubstituierte plumbane. Synthese, eigenschaften und NMR-Spektren der verbindungen (CF3)nPbR4-n (n = 1–3) und (C
  作者：R. Eujen、A. Patorra

  DOI：10.1016/0022-328x(92)88006-5

  日期：1992.10

  Trifluoromethylated derivatives of lead, (CF3)nPbR4-n (n = 1–3; R = CH3, C2H5), have been prepared by a stepwise halide/CF3 exchange from (CF3)nPbR3-nX (n=O–2) and donor-stabilized (CF3)2Cd. Upon treatment of CF3PbR3 and (CF3)2PbR2 with halides under mild conditions, selective cleavage of the PbC(H) bond and formation of the corresponding alkyl(trifluoromethyl)haloplumbanes were achieved, whereas

  铅的三氟甲基化衍生物（CF 3）n PbR 4- n（n = 1-3; R = CH 3，C 2 H 5），是通过从（CF 3）n PbR逐步进行卤化物/ CF 3交换制得的3- n X（n = O-2）和施主稳定的（CF 3）2 Cd。处理CF 3 PbR 3和（CF 3）2 PbR 2时用卤化物在温和的条件下，PbC（H）键的选择性裂解和相应的烷基（三氟甲基）卤代铅烷的形成得以实现，而仅用（CF 3）3 PbMe（CF 3）2 PbMeX得到了。对于系统PbR 4 /（CF 3）n E（E = Hg，Ge，Sn），（CF 3）4 Sn是最有效的CF 3转移试剂，观察到烷基和三氟甲基的直接交换。所有化合物均通过振动，质谱和多核NMR光谱表征。NMR耦合常数n J（207已确定了PbE）（E = 19 F，1 H，13 C），其随溶剂和取代基的变化而变化，并确定了它们的绝对符号。之间发现线性关系1
• Tri(tert-butyl) plumbyl derivatives of Group 14 elements multinuclear magnetic resonance studies: Determination of coupling signs
  作者：Max Herberhold、Volker Tröbs、Bernd Wrackmeyer

  DOI：10.1016/s0022-328x(97)00090-9

  日期：1997.8

  coupling constants nJ(207Pb,13C) (n = 1, 2), 1J(207Pb,29Si), 1J(207Pb, 19Sn) and 1J(207Pb, 207Pb) were determined by appropriate 1D heteronuclear double resonance experiments and 2D heteronuclear shift correlations. The influence of the tBu3Pb group on the bonding situation is reflected by sign changes of several coupling constants when compared with analogous trimethyllead derivatives.

  通过使六（叔丁基）二lum烷（1）与过量的锂反应来制备三（叔丁基）铅基锂在THF（2）中的溶液。用多种第14组亲电试剂处理该试剂可得到四有机油酸酯化合物t Bu 3 Pb-R（3，R = Me（a），Et（b），n Pr（c），n Bu（d），CH 2 Ph （e），CH 2 SiMe 3（f）），铅基硅烷t Bu 3Pb-SiR 2 1 R 2（4，R 1 = R 2 = Me（a），R 1 = Me，R 2 = t Bu（b），R 1 = Me，R 2 = SiMe 3（c），R 1 = Me，R 2 = Ph（d），R 1 = R 2 = Ph（e）），1铅ger锗烷t Bu 3 Pb-GeMe 3（5a），铅stan庚烷t Bu3 Pb-SnR 3 3（6，R 3 = Me（a），Et（b），n Bu（c），t Bu（d），Ph（e），1,1'-二茂铁基（f）），和hexaorganodiplumbanes
• Metal-halogen bonding studies with group IV A trialkylmetal halides
  作者：Edwin C. Friedrich、Charles B. Abma、Paul F. Vartanian

  DOI：10.1016/s0022-328x(00)81789-1

  日期：1980.3

  Halogen redistribution reactions have been found to take place between benzyl bromide or benzyl iodide and the Group IVA silicon, germanium, tin, and lead containing triakylmetal chlorides. However, for the reactions of the Si, Ge and Sn compounds, a quaternary ammonium halide catalyst was necessary to enable the equilibria to be established at reasonably rapid rates. The equilibrium constants at 50°C

  已经发现卤素重新分布反应发生在苄基溴或苄基碘与IVA族硅，锗，锡和含铅的三烷基金属氯化物之间。但是，对于Si，Ge和Sn化合物的反应，季铵卤化物催化剂对于使平衡能够以合理的快速速率建立是必不可少的。在这些卤素的重新分布下，已分别测量了在50°C时的平衡常数。已发现它们在IV A组中从硅到铅下降时逐渐增加，对于R 3 MCl + BzBr和R 3而言，在硅中小于1，而在铅中大于1。 MCl + BzI反应。该Δ ģ°，这些均衡值已被计算出，并建议他们的差异可能在的相对重要性来解释p π d在各种IV族甲trialkylmetal卤化物系统的卤素-金属粘合π贡献。
• Gruettner; Krause, Chemische Berichte, 1916, vol. 49, p. 1129
  作者：Gruettner、Krause

  DOI：——

  日期：——